2 Flashcards
- An advantage of celecoxib over most NSAIDs is:
a. Less inhibition of PGE2 effects on gastric
mucosa
b. Less risk of bronchospasm and
hypersensitivity reactions
c. Greater degree of efficacy in the
treatment of rheumatoid arthritis
d. Less risk of harm to the developing fetus in
third trimester
a. Less inhibition of PGE2 effects on gastric
mucosa
The most prescribed DMARD that affect the
leukocyte suppression, decreasing the
inflammation that results from immunologic byproducts:
a. Sulfasalazine
b. Leflunomide
c. Hydroxychloroquine
d. Methotrexate
d. Methotrexate
Which of the following anti-gout medications acts by decreasing serum levels but increasing urine
levels of uric acid thus increasing the risk of kidney stone development?
a. Rasburicase
b. Colchicine
c. Allopurinol
d. Probenecid
d. Probenecid
This drug for rheumatoid arthritis inhibits pyrimidine
synthesis, which reduces lymphocyte proliferation
and modulation of inflammation:
a. Nabumetone
b. Sulfasalazine
c. Meloxicam
d. Leflunomide
d. Leflunomide
This treatment of gout is reserved for patients with insufficient relief, intolerance, or contraindications
to NSAIDs:
a. Prednisone
b. Allopurinol
c. Sulindac
d. Colchicine
e. Probenecid
d. Colchicine
Which of the following are the criteria for
classification of rheumatoid arthritis (ARA)?
I. Radiographic changes
I. Arthritis of hand joints
Ill. Rheumatoid nodules
IV. Serum rheumatoid factor
a. II, Ill, IV
b. II, III
c. Ill, IV
d. I, II, III, IV
e. I, III
d. I, II, III, IV
A 54-year-old woman presented with signs and symptoms consistent with an early stage of rheumatoid arthritis. The decision was made to initiate NSAID therapy. Which of the following patient characteristics is the most compelling
reason for avoiding celecoxib in the treatment of
her arthritis?
a. History of myocardial infarction
b. History of gout
c. History of alcohol abuse
a. History of myocardial infarction
This drug for osteoporosis inhibits bone resorption
and increase bone density:
a. Zoledronic acid
b. Raloxifene
c. Calcitonin
d. Teriparatide
a. Zoledronic acid
The intramuscular route of corticosteroid is
preferable in nonadherent rheumatoid arthritis
patients. An example of corticosteroid in depot
form is/are:
I. Triamcinolone acetonide
Il. Triamcinolone hexacetonide
Ill. Prednisone
IV. Methylprednisolone acetate
a. I, II, III
b. II, IV
c. I, II, IV
d. II, III, IV
e. II, III, IV
c. I, II, IV
SERM useful for treating osteoporosis:
a. Raloxifene
b. Clomifene
c. Anastazole
d. Exemestane
e. Toremifene
a. Raloxifene
- Which of the following are causes of secondary
osteoporosis?
I. Endocrine disorders
Il. Genetic/ Congenital
Ill. Postmenopausal
IV. Medications
a. II, III, IV
b. I, II, III
c. I, III, IV
d. II, III, IV
e. I, II, IV
e. I, II, IV
An antihyperuricemic agent that is the drug of
choice in patients with a history of urinary stones
or impaired renal function:
a. Colchicine
b. Prednisone
C. Probenecid
d. Allopurinol
e. Sulindac
a. Colchicine
- The following is/are true on Type Il Senile
Osteoporosis:
I. Occurs in men and women older than age 70
II. The most common fractures are hip, pelvic and
vertebral
Ill. There is a proportional loss of cortical and
trabecular bone
IV. It is secondary to other conditions
a. I, III, IV
b. I, II, III
c. II, III, IV
d. I, II, III, IV
e. II
d. I, II, III, IV
- In a patient who has had documented gouty
arthritis and hyperuricemia and who also has hypertension, a preferred antihypertensive agent
would be:
a. Clonidine
b. HCTZ
c. Lisinopril
d. Losartan
d. Losartan
- Biologic DMARD:
I. Etanercept
II. Adalimumab
Ill. Anakinra
IV. Infliximab
a. I, III, IV
b. I, II, III, IV
c. II, IV
d. I, III
e. II, III, IV
b. I, II, III, IV
