2 Flashcards
Phases of Cardiac cycle
Mid to late ventricular diastole
Isovolumetric contaction
Mid to late ventricular systole/ ventricular ejection phase
Isovolumetric relaxation
Factors influencing EDV
Venous Return
Venomotor tone (venous constriction)
Muscle milking
Respiratory pump
Factors influencing Preload
EDV
HR (FILLING TIME)
Factors influencing stroke volume
Preload
Contractility
Afterload
What is Frank-Starling’s law
Greater the stretch on heart, greater the contraction
Factors influencing cardiac output
Stroke volume
Heart rate
Factors influencing SV
Preload
Afterload
Contractility
Factors influencing TPR
Blood viscosity
Types of vessels
Radius of vessel
Factors influencing HR
Sympathetic nervous System (B1&2, +)
Parasympathetic nervous System (M2, -)
Thyroid hormones (T3&4, +)
Drugs
Calcium (+)
Potassium (-)
Body temperature (+)
Peripheral chemoreceptors
Age
Gender
What is compliance
Ability to stretch during blood flow
=∆V÷∆P
Factors influencing capillary fluid exchange
Hydrostatic Pressure (P)
Oncotic Pressure (π)
Formula for net capillary pressure
NP = (Pc -Pi) + (πi - πc)
3RD SPACING
movement of fluid to areas fluid shouldn’t be due to excess capillary leaking, eg ascites, pleural effusion
Factors influencing PV LOOP
Preload
Afterload
Contractility
Compliance
What is PV LOOP
Graph showing LV pressure against volume throughout the cardiac cycle
Graph is square shaped
Area under graph shows cardiac workload