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Biochem2 > 2 > Flashcards

2 Flashcards

1
Q

1.
Which statement/s is/are correct about enzymes?
a. Each human enzyme has the same optimum DH
b. All proteins are enzymes
c. The molecule which is converted by an enzyme is called substrate
d. Most human enzymes have a length of less than 50 amino acids.

A

C

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2
Q
  1. Which factor/s can be considered as non-specific activator/s for enzymes?
    a. Insulin
    b. Proteolytic cleavage
    c. pH
    d. CO2
A

C, D

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3
Q
  1. Allosteric regulation can be described as:
    a. Effector binds just at active site
    b. Effector binds at the site other than the active site
    c. Effector binds to protein usually covalently
    d.Effector binding results in a conformational change
A

B

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4
Q
  1. Which enzyme/s is/are hydrolases?
    a. Elastase
    b.Carboxypeptidase A
    c.Citrate synthase
    d. Hexokinase
A

A, B

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5
Q
  1. Which statement about peptidases is/are correct?
    a.Exo-peptidases cleave at the ends of the molecule
    b. Exo-peptidases split the carbohydrates in the middle of molecule
    c. Endo-peptidases split the carbohydrates in the middle of molecule
    d. Endo-peptidases cleave at the ends of the molecule
A

A

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6
Q
  1. Which enzymes are found in the pancreatic juice?
    a. Carboxypeptidase B
    b.Elastase
    c.Pepsin
    d.sucrase
A

A, B

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7
Q
  1. Which statement about the bile is correct?
    a. It cleaves ester bonds in fat molecules
    b.It ensures emulsification
    c.Bile acids are structurally similar to cholesterol
    d.All three answers are correct
A

D

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8
Q
  1. Which are the enzyme/s of glycolysis?
    a.Glucose-6-dehydrogenase
    b.Hexokinase
    c.Pyruvate decarboxylase
    d. Pyruvate kinase
A

B, D

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9
Q
  1. In glycolysis, fructose-6-phosphate is made from
    a. acetyl-CoA
    b. fructose
    c. fructose-1-phosphate
    d. glucose-6-phosphate
A

D

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10
Q
  1. What is/are the components of the Krebs cycle?

a. 1,3-biphosphoglycerate
b. fumarate
c. hexokinase
d. succinate

A

B, D

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11
Q
  1. Which statements about alpha-ketoglutarate dehydrogenase complex is/are correct?

a. it forms a thioester bond
b. it’s similar to pyruvate dehydrogenase complex
c. Vitamins A and C are active intermediates
d. All of these answers are correct

A

B

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12
Q
  1. Decarboxylation reaction in the Krebs cycle is/are catalyzed by:

a. fumarate
b. alpha-ketoglutarate dehydrogenase
c. isocitrate dehydrogenase
d. malate dehydrogenase

A

B

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13
Q
  1. What is the main function of oxidative phosphorylation?

a. consumption of oxygen
b. biosynthesis of NADH
c. heat production
d. production of ATP

A

D

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14
Q
  1. Pentose phosphate pathway takes place in:

a. cytosol
b. mitochondrial matrix
c. inner membrane of mitochondria
d. endoplasmic reticulum

A

A

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15
Q

Which statement for fatty acid synthesis is/are incorrect?

a. ketoacyl-CoA reductase needs NADH as a coenzyme
b. in each cycle of FA synthesis 2 CO2 molecules are released
c. fatty acid is elongated by 2 carbon atoms in each cycle
d. malonyl-CoA is used in each cycle

A

B

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16
Q

Which coenzyme is/are produced in fatty acid beta-oxidation?

a. FADH2
b. NADPH
c. NADH and H+
d. all answers are correct

A

C

17
Q

In fatty acid beta-oxidation each cycle, c=c double bond arises, to continue the cycle what is added to c=c?

a. CO2
b. H2O
c. phosphate
d. coenzyme A

A

D

18
Q

Krebs cycle takes place in:

a. cytosol
b. the inner membrane of mitochondria
c. mitonchondria
d. endoplasmatic reticulum

A

C

19
Q

What are the products of oxidative phosphorylation?

a. citrate
b. NADH
c. ATP
d. acetyl-CoA

A

B, C

20
Q

Which reaction is catalyzed by malate dehydrogenase?

a. Conversion of fumarate to succinate
b. Conversion of malate to succiate
c. Conversion of malate to fumarate
d. Conversion of malate to oxaloacetate

A

D

21
Q

??Decarboxylation in the Krebs cycle is/are catalyzed by:
a. malate dehydrogenase
b. fumarase
c. isocitrate dehydrogenase
d. alpha-ketoglutarate dehydrogenase

A

D

22
Q

What are the enzyme/s of glycolysis:

a. Pyruvate decarboxylase
b. Hexokinase
c. Pyruvate kinase
d. Glucose-6-dehydrogenase

A

B, C

23
Q

Fructose-6-phosphate in glycolysis is made from

a. Glucose-6-phosphate
b. Fructose
c. Fructose-1-phosphate
d. Acetyl-CoA

A

A

24
Q

In glyceraldehyde-3-phosphate dehydrogenase catalysed reaction

a. The product is 1,2 bisphosphoglycerate
b. The product is 1,3-bisphosphoglycerate
c. The product is 1,6-bisphosphoglycerate
d. The product is 3,6-bisphosphoglycerate

A

B

25
Q

Which metal ion/s is required for hexokinase activity?

a. Fe2+
b. Cu2+
C. Na+
d) Mg2+

A

D

26
Q

Which are the non-reversible steps of glycolysis?

a. 1:10:4
b. 2;3;7
c. 2:7:9
d. 1;3;10

A

D

27
Q

The product/s of the fermentation process is/are:

a. CO2
b. Lactate
c. Pyruvate
d. Ethanol

A

A, D

28
Q

What are the functions of bile?

a. to emulsify the lipid molecules
b. to help with fat solubel vitamin absorption
c. to cleave ester bonds
d. all answers are correct

A

D

29
Q

Which statement about carboxypeptidase is/are correct?

a. They use the water to break down the bonds
b. Secreted in the small intestine
c. They belong to exo-peptidases
d. Are found in the gastric juice

A

C

30
Q

Which statement/s about phospholipases is/are correct?

a. Breaks down glycerophospholipids
b. Acts on ester bonds
c. Releases monoglycerate as product
d. All answers are correct

A

D

31
Q

What is the optimal pH range for the salivary amylase?

a. 6 8-7.2
b. 2.1-3.2
c. 8.9-9.3
d. all answers are correct

A

A

32
Q

Which enzyme/es are secreted in pancreatic juice?

a. Lactase
b. Colipase
c. Nucleosidase
d. Chymotrypsin

A

D

33
Q

Allosteric regulation can be described as:

a. Effector binds at the active site
b. Effector binding at a site other than the active site
c. Usually, the effector binds to protein covalently
d. Effector binding results in conformational channel

A

B

34
Q

Non-competitive inhibitor:

a. Binds only to ES complex
b. Usually does not affect the binding of the substrate
c. Decrease enzyme activity by reduction
d. All answers are correct

A

D

35
Q

Specific activators of enzymes are:

a. Similar in structure to substrate
b. Compete for the same binding site with
c. Binds only covalently to enzyme
d. All answers are wrong

A

A

Biochem2 (1 decks)

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