1st Year Common Clinical Drugs Flashcards
Local Anesthetic
Generic Name: lidocaine
Trade Name: Xylocaine
Concentration: 20mg/mL (0.2%)
Per kg Dose: ≤ 1mg/kg
Common Adult Dose: Up to 100mg
Narcotic/opioid
Generic Name: meperidine
Trade Name: Demerol
Concentration: Variable
Per kg Dose: 0.5-2mg/kg
(10x morphine dose)
Common Adult Dose: 25mg for shivering
Analgesic & Sedative
Generic Name: dexmedetomidine
Trade Name: Precedex
Concentration: Vial 200mcg/2mL
Bolus Dilution: 4mcg/mL
Infusion Dilution: 4mcg/mL
Per kg Dose: —
Common Adult Dose:
Loading dose: 1mcg/kg over 10 min
Infusion: 0.2-0.7mcg/kg/hr
Bolus: 20mcg
To dilute: Add 200mcg/2mL to 50mL syringe of LR = 4mcg/mL
Add 400mcg/4mL to 100mL bag of LR = 4mcg/mL
Reversal Agent for Nondepolarizers
Generic Name: sugammadex (most effective reversal)
Trade Name: Bridion
Concentration: 100mg/mL (10%)
Per kg Dose: 16mg/kg for failed airway
4mg/kg for 2 twitches
2mg/kg for 4 twitches
Common Adult Dose: 200mg
Anticholinergic/Antimuscarinic (vagolytic)
Generic Name: glycopyrrolate (3mL syringe)
Trade Name: Robinul
Concentration: 0.2mg/mL
Per kg Dose: 0.01-0.02mg/kg
Common Adult Dose: ↑HR dose = 0.2mg
Reversal dose = 1mL (0.2mg) per 1mL (1mg) Neostigmine
Anticholinergic/Antimuscarinic (vagolytic)
Generic Name: atropine
Trade Name: Atropine
Concentration: 0.4mg/mL
Per kg Dose: 0.01-0.03mg/kg
Common Adult Dose: Same dosing as Robinul, but more powerful HR effects
Antiemetic
Generic Name: dexamethasone (3mL syringe)
Trade Name: Decadron
Concentration: 4mg/mL
Per kg Dose: —
Common Adult Dose: Antiemetic dose: 4mg(1mL)
Swelling dose: 8-12mg
Vasopressor [Alpha 1 Agonist (vasoconstrictor){raises BP}]
Generic Name: phenylephrine
Trade Name: Neosynephrine
Concentration: 10mg/mL
Dilute to 100mcg/mL
(10mL syringe)
Per kg Dose: —
Common Adult Dose: Start at 50-100mcg
Dilute into 10mL syringe: Add 1000mcg/0.1mL = 1000mcg/10mL = 100mcg/1mL
Dilute into 250mL bag: Add 10mg/1mL = 40mcg/mL for infusion
Nondepolarizing Muscle Relaxant
Generic Name: rocuronium
Trade Name: Zemuron
Concentration: 10mg/mL (1%)
Per kg Dose: 0.6-1.2mg/kg
Common Adult Dose:
Normal intubation: 30-50mg
RSI: 1.2mg/kg
Re-dosing: 10-20mg
Sedative/anxiolytic
Generic Name: midazolam
Trade Name: Versed
Concentration: 1mg/mL (0.1%)
Per kg Dose: —
Common Adult Dose: 1-2mg
Narcotic/opioid
Generic Name: sufentanil
Trade Name: Sufenta
Concentration: Vial: 50mcg/mL
Dilute to 5mcg/mL
Per kg Dose: 0.05-0.1mcg/kg for induction
Common Adult Dose: 1/10 fentanyl dose
2.5-5mcg boluses titrated to respiratory rate or vital sign
To dilute add 50mcg/1mL to 9mL syringe of LR
Narcotic/opioid
Generic Name: morphine
Trade Name: Morphine
Concentration: Variable
Per kg Dose: 0.05-0.2mg/kg
Common Adult Dose: Up to 10 total mg
NSAID analgesic
Generic Name: ketorolac
Trade Name: Toradol
Concentration: 15-30mg/mL (1.5-3%)
Per kg Dose: 0.5-0.75mg/kg
Common Adult Dose: Half the dose if >70yo
Induction Agent
Generic Name: propofol
Trade Name: Diprivan
Concentration: 10mg/mL (1%)
Per kg Dose: Induction: 1.5-2.5mg/kg
Sedation: 25-150mcg/kg/min
GA TIVA: 150-300mcg/kg/min
Common Adult Dose: —
Induction Agent
Generic Name: ketamine
Trade Name: Ketalar
Concentration: Variable
Per kg Dose: 1-2.5mg/kg
Common Adult Dose: —
Depolarizing Muscle Relaxant
Generic Name: succinylcholine (10mL syringe)
Trade Name: Anectine
Concentration: 20mg/mL (2%)
Per kg Dose: 1-2mg/kg
Common Adult Dose: 60-200mg
Antiemetic
Generic Name: ondansetron (3mL syringe)
Trade Name: Zofran
Concentration: 2mg/mL
Per kg Dose: 0.15mg/kg
Common Adult Dose: Up to 4-8mg (most often 4mg)
Narcotic/opioid
Generic Name: fentanyl (3 or 5mL syringe)
Trade Name: Sublimaze
Concentration: 50mcg/mL
Per kg Dose: 0.5-1mcg/kg for induction
Common Adult Dose: 25-50mcg boluses titrated to respiratory rate or vital signs
Narcotic/opioid
Generic Name: hydromorphone
Trade Name: Dilaudid
Concentration: (SLH) 2mg/mL (5mL syringe)
Dilute to 0.5mg/mL
Per kg Dose: —
Common Adult Dose: Up to 1-2 total mg
To dilute to 0.5/mL add 2mg/1mL to 3mL syringe of LR
Induction Agent
Generic Name: etomidate (10mL syringe)
Trade Name: Amidate
Concentration: 2mg/mL (0.2%)
Per kg Dose: 0.3-0.4mg/kg
Common Adult Dose: Up to 20mg
Vasopressor [mostly raises BP (stronger than phenylephrine)]
Generic Name: norepinephrine
Trade Name: Levophed
Concentration: 4mg/4mL
Dilute to 16mcg/mL
Per kg Dose: —
Common Adult Dose: 4-16mcg
To dilute to 16mcg/mL add 4mg/4mL to 250mL bag
To dilute to 4mcg/mL add 4mg/4mL to 1000mL bag
Vasopressor [Alpha 1 & Beta 1 Agonist (raises HR & BP)]
Generic Name: ephedrine
Trade Name: Ephedrine
Concentration: 50mg/mL Dilute to 10mg/mL (5mL syringe)
Per kg Dose: —
Common Adult Dose: Start at 5-10mg
To dilute to 10mg/mL add 50mg/1mL to 4mL syringe of LR
Beta Blocker [beta 1 antagonist (↓s HR)]
Generic Name: metoprolol
Trade Name: Lopressor, Toprol
Concentration: 1mg/mL (0.1%)
Per kg Dose: —
Common Adult Dose: Start at 1-5mg
Narcotic/opioid
Generic Name: remifentanil
Trade Name: Ultiva
Concentration: 1mg powder
Dilute to 50mcg/mL
Per kg Dose: Start at 0.1mcg/kg/min
Common Adult Dose: —
To Dilute: Add 2mg powder to 40mL of LR = 50mcg/mL
Vasodilator (↓s BP)
Generic Name: Hydralazine
Trade Name: Apresoline
Concentration:
Per kg Dose: 20mg/mL (2%)
Common Adult Dose: Start at 5-10mg
Beta Blocker [alpha 1 & beta 1 antagonist (↓s HR & BP)]
Generic Name: labetalol
Trade Name: Trandate
Concentration: 5mg/mL (0.5%)
Per kg Dose: —
Common Adult Dose: Start at 5mg
Beta Blocker [beta 1 antagonist (↓s HR)]
Generic Name: esmolol
Trade Name: Brevibloc
Concentration: 10mg/mL (1%)
Per kg Dose: —
Common Adult Dose: Start at 10-50mg
raises HR & BP (stronger than ephedrine)
Generic Name: epinephrine
Trade Name: Adrenaline
Concentration:
Ampule: 1:1000 or 1mg/mL
Dilute: 10mcg/mL (Bolus Little)
or Dilute: 100mcg/mL
Dilute: 4mcg/mL (Infusion)
Per kg Dose: —
Common Adult Dose:
10-50mcg (vasopressor)
-Up to 1mg (cardiac arrest)
To Dilute to:
100mcg/1mL: Add 1mg/1mL to 9mL syringe of LR: 1000mcg/10mL = 100mcg/1mL
10mcg/1mL: Using previous syringe (100mcg/1mL) add 100mcg/1mL to 9mL syringe of LR: 100mcg/10mL = 10mcg/1mL
4mcg/1mL: Add 1mg/1mL to 250mL bag of NS = 4mcg/1mL