1st test Flashcards

1
Q

SIRIM

A
Acronym for diagnosing a pathologies stands for
S tructueal
I mmune
R eactive
I nfectious
M etabolism
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2
Q

structural processes

A

usually long standing and unchanging
Slow to Develop
often found in young patients

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3
Q

Immune processes

A

Responds to steroids
itching/pain- allergy or autoimmune
more seen in women… classic signs of inflammation(shares with infectious processes)

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4
Q

reactive process

A

Should resolve when causative agent goes away

may mimic neoplasm

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5
Q

metabolic process

A

are usually a systemic condition
maybe Hormonal, Nutritional or Genetic
Ex: iron deficiency anemia

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6
Q

Iron deficiency anemia is an example of what kind of pathological process

A

metabolic

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7
Q

Infectious

A

Responds to ANTI-MICROBIALS

may look like Tumor and is often Painful

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8
Q

Herpes is an example of what kind of process

A

Infectious process

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9
Q

Neoplastic processes

A

Benign: encapsulated, mimics structural process

Malignant: Not encapsulated, grows rapidly, mimics infection; ill defined mass, enlarge lymph nodes(also seen in infections)

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10
Q

Recite color differences and meanings

A

White- less blood visble could be:
Psuedomembrane,Thick or callous epithelium, scarred fibrous tissues

Lipid

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11
Q

frenum tag is a example of a

A

structural

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12
Q

true of false

candidaisis is a common cause of burning sensation

A

true

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13
Q

If tissue or tumor moves freely then it is most likely

A

Benign

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14
Q

Induration means

A

Fixed to surrounding area

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15
Q

Differential Diagnosis

A

list of Diseases with features consistent with the observed signs and symptoms

Arranged in order of probability, as determined y epidemiology and frequency of occurance

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16
Q

dentigerous cyst

A

most common radiolucency in impacted tooth

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17
Q

the most probably diffential diagnosis is

A

Working diagnosis— dictates treatment plan.

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18
Q

What is the most common oral fungal infections in humans

A

Candidiasis

usually does not cause harm

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19
Q

overuse of topical steroids or diabetes can lead to

A

candidiasis

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20
Q

symptoms of candidiasis

A

burning sensation/unpleasant taste of the mouth

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21
Q

Burning mouth syndrome

A

burning of the mouth ongoing/re-curring with NO OBVIOUS CAUSE.

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22
Q

what is the most common form of candidiasis

A

acute pseudomembranous candidiasis

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23
Q

chronic atrophic/ erythematous

A

Red in color in special sites:
Angular cheilitis
median rhomboid glossitis - red area on dorsom of tongue
chronic mucocutaneous -

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24
Q

mucocucutaneous-

A

seen in oral cavity and skin, not common

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25
Q

Psuedomembranous candidiasis

A

white in color, removed by scraping.leaving underlying tissue erythamatous

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26
Q

Median Rhomboid Glossitis

A

red in color, center of the tongue atrophy, loss of filiform papilla

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27
Q

denture stomatitis

A

to long denture, petechiae

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28
Q

Chronic hyperplastic candidiasis

A

White patch cant be scraped off ( candidal leukoplakia)

leukoplakia associated

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29
Q

what is the clinical significant form of candidas

A

hyphae

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30
Q

how is candidiasis treated

A
Antifungals:
nystatin
clotrimazole
ketoconazole
fluconazole
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31
Q

Histoplasmosis usually begins where

A

Lungs inhaled spore

large deep seated non healing ulcer

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32
Q

tramatic ulcerative granulama with stromal

A

mimics squamous cell and microbial ulcer

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33
Q

what is the most common systemic deep fungal infection in the US

A

Histoplasmosis

endemic in ohio and mississippi

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34
Q

Blastomycosis

A

Pseudoepitheliomatous hyperplasia is characteristic— often misdiagnosd as SCC

also known as blasomyces

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35
Q

cryptococcosis

A

most common life threatening fungal infection in AIDS patients

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36
Q

zygomycosis/mucormycosis/phycomycosis

A

starts as ulcer rapidly progresses, seen in palate& sinuses… causes necrosis of the palate.
most common deep fungal infection in un controlled insulin dependent diabetes … non septate hyphae

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37
Q

Aspergillosis

A

Allergic reaction in normal host
also called allergic fungal sinusitis
2nd most common after candididasis

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38
Q

HHV-4

A

Ebstein-Bar Virus(EBV)

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39
Q

HHV-3

A

varciella zoster visurs

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40
Q

primary herpes infection in young children

A

cause gingivastomatitis

41
Q

Primary herpes infection in adults

A

1st sign sore throat- pharyngotonsilitis

42
Q

all disease that start as a vesicle and end in a ulcer after a couple days are

A

Vesiculobulous/ vesicle ulcerative

43
Q

Tzanck cells are characteristic of

A

Acantholysis-loss of cellular cohesion

diagnosed by cytologic smear &tissue biopsy

44
Q

diagnose Acantholysis with

A

smear or biopsy

45
Q

what is the number one cause of infectious blindness is Us

A

herpes in eye- autoinoculation

46
Q

Herpes zoster

A

shingles, unilateral, extreme pain

47
Q

Ramsay Hunt Syndrome

A

extreme herpes zoster that will send patient into paralysis

48
Q

infectious mononucleousis

A

kissing disease caused cause by EBV
lymphadnopathy,
ANUG LESIONS

49
Q

HHV-5

A

Cytomegalovirus

50
Q

cytomegalovirus

A

seen in children/ immunocompromised

– possible encephalitis

51
Q

What fungal organism causes candidiasis

A

Candida albicans

52
Q

what form of candida albicans is dangerous

A

hyphae

53
Q

which is most common candiasis

A

erythematous candidiasis- usually follows antibiotic therapy

psuedomembrane- most common identified

54
Q

chronic hyperplastic candidiasis

A

also called candidal leukoplakia
least common type of candida
characterized by white patch that cannot be removed by scraping
diagnosed by presence of cardinal hyphea

55
Q

What is bacteria is the most common systemic Fungal infection in the US

A

Histoplasmosis- yeast at body temp
acute- pulmonary infection -self limiting
chronic-less common affects lungs

56
Q

hypoadrenocortisolism

A

Addisons disease

57
Q

blastomycosis

A

uncommon disease cause by blastomyces dermatidis -spores

seen more in men do to outdoor activity in the east coast and Great Lake area

58
Q

cryptococcosis

A

fungal disease tragic in AIDs/ immunocompromised patients. less common since AIDs treatment… caused by c.neoformans found in pigeon poop worldwide

59
Q

What is Keratoacanthoma

A

self-healing Carcinoma
self -limiting
Does not occur intraorally

60
Q

how is Keratoacanthoma described

A

Firm non tender, dome shaped nodule with central keratin plug

61
Q

Oral melanotic macule

A

focal increase in melanin unrelated to solar exposure. More in women..
Solitary uniform tan to dark-brown, round, oval macule/ less than 7 mm do not enlarge

62
Q

Melanocytic Nevus

A

Nevus- Congenital/ developmental

63
Q

what is the most common acquired nevus

or Common mole

A

Melanocytic Nevus

64
Q

True of false Melanoma can arise from nevi

A

true (believe it or not)

65
Q

Verruca Vulgaris

A

HPV 2, 4, 40
can spread by autoiinoculation
benign, focal hyperplasia of squamoua epithelium
Frequent in children seen on hands
in adults: vermillion , labial mucosa or anterior of tongue

66
Q

how is verruca Vulgaris wart seen

A

as paineless papules or nodules with papillary projections ; occur in clusters . 2/3 disappear within 2yrs
* Form Koilocytes - hyperchromatic nuclei, clear perinuclear halo

67
Q

Seborrheic Keratosis

A

due to chronic sun exposure

acquired benign proliferation of epithelial hyperplasia

68
Q

seborrheic keratosis is characterized by

A

mulltiple small tan to brown macules initially , become papillaru raised, usually less than 2 cm
not removed
appears “stuck onto” skin

69
Q

Keratoacanthoma

A

Self limiting
EXTREMELY DIFFERENTIATED squamou cell carcinoma call SCC “ Keratoacanthoma type”
rarely b4 age 45, male
does not occur intra orally

70
Q

Proliferative Verrucous Leukoplakia characterized by

A

extensive quite plaques , multiple sites, invariable progression-HPV16-Recur after excision.

4:1 female dominant usually non smokers and non drinkers

71
Q

Erythroplakia

A

Red patch that cannot be clinically or pathologically diagnosed as other condition
Suspicious red lesion observe for 10-14days b4 biopsy is needed

72
Q

Histologic spectrum of erythroplakia

A

mild dysplasia -10%
carcinoma in situ- 40%
Invasive Carcinoma-50%

73
Q

actinic cheilitis

A

diffuse premalignant alteration of lower lip vermillion
rough scaly area on drier portions of vermillion
degeneration of collagen fibers

74
Q

Lip Vermillion Carcinoma

A

Due to chronic ultraviolet radiation
90% on lower lip
slow growing

75
Q

intral oral SCC location frequencies

A

90% floor of mouth , soft palate anterior tonsillar pillar complex,ventral/lateral border of tongue

  • Most common - posterior lateral & ventral surfaces of tongue followed by floor of mouth

20% on anterior lateral or ventral tongue,
only 4% on dorsum

76
Q

in tumor stagein/ classifyining TMN system stand for what

A

T- tumor size (T1=smallest- T4= largest)
N- spread to local lymph nodes
M- Presence or absence of distant metastasis

77
Q

grading a tumor means

A

judging degree of tumor resembleance to parent tissue
low grade - still resembles parent (1)
high grade (III/IV) - poorly differentiated

78
Q

Verrucous Carcinoma

A

Snuff dippers cancer- painless well demarcated thick white/pink papillarty
low grade variant of SCC, predominantly in men 55+
extensive and often present 2-3ys b4 diagnosis

79
Q

Rodent ulcer

A

Basal cell carcinoma

80
Q

Ranula

A

Mucocele in the floor of the mouth
blue , dome-shaped, fluctuant swelling
Larger than mucoceles

81
Q

How is Ranula treated

A

Marsupialization (slit absess and make continueous) or removal of gland

82
Q

Salivary duct cytst

A

true cyst line by epithelium
resemble mucocele
frequent on FlO OF mouth, buccal mucosa and lips

83
Q

Sialothiasis

A

Calcified structures within salivary ducts
episodic pain or swelling of affected gland, especially at mealtime
build up of Ca+ around nidus of debris
most common in subman gland (whartons duct)

84
Q

Plasma cell Gingivitis. is seen in

A

Contact stomatitis in gingiva frequent site

85
Q

contact stomatitis

A
characterized by pain and burning
Plasma cell gingivitis 
clinically varies 
toothpaste reaction gives diffuse pattern
chewing gum/  candy gives localized.
often to cinnamon flavoring
86
Q

Melkersson-Rosenthal syndrome

A

Orafacial granulomatosis

when combined with facial paralysis and fissure tongue

87
Q

cheilitis Granulomatosa

A

Orafacial granulomatosis

involving lips alone

88
Q

In all orafacial granulomatosis

A

60% resolves from elimination of oral infection or allergy
Systemic/ intra lesion steroids control progression
Lesions resolve spontaneously without treatment

89
Q

Melkersson-Rosenthal syndrome

A

orofacial granuloma

Accompanied by facial paralysis and fissured tongue

90
Q

chelitis granulomatosa

A

orofacial granuloma involing the lips alone

91
Q

Plasma cell gingivitis is seen in what

A

contact stomatitis .. allergy to cinnamon or other flavoring when it affects ginviga which is often

92
Q

Herpangina

A

Caused by Coxsackie Virus A
multiple ulcers on soft palate/ tonsillar
Begins as red macule that then form vesicles and ulcerate
sore throat- similar to strep
limited to oral cavity

93
Q

measles is what virus

A

Paramyxovirus - also mumps(swollen parotid bilateral)

94
Q

Koplik spots

A

are the clinical oral features of measles

95
Q

linear gingiva erythema

A

is a manifestation of HIV

free gingival margin extending 2mm apically

96
Q

HHV-8

A

Kaposi sarcoma

97
Q

special stains used to identify amyloid

A

Congo red dye & Crystal Violet stain

98
Q

Pyostomatitis vegetans

A

unusual oral expression of IBD…Ulcerative colitis or Crohns Disease
Yellow linear serpentine pustules on eythamatous oral mucosa
“Snail track” Ulcerations

99
Q

Hypophosphatasia

A

decrease alkaline phosphatase
decrease cementum
early loss of teeth opposite of pagets