1st Line Treatment/2nd Ppx of opportunistic infections

Question 1

Cryptococal meningitis Tx 1 + 1

Answer 1

Amphotericin B deoxycholate + flucytosine

Question 2

CMV Retinitis Tx 1 or 1

Answer 2

Valganciclor or ganciclovir

Question 3

MAC Tx 1 or 1 + 1 +/- 1

Answer 3

Clarithromycin or azithro + ethambutol +/- rifampin/rifabutin

Question 4

PCP Tx 1+/- 1

Answer 4

TMP/SMX +/- corticosteroids

Question 5

Toxoplasmosis meningoencephalitis Tx 1 + 1

Answer 5

Pyrimethamine + sulfadiazine

Question 6

Cryptococal meningitis 2nd ppx 1

Answer 6

Fluconazole (low dose)

Question 7

CMV retinitis 2nd ppx 1 or 1

Answer 7

Valganciclovir or ganciclovir (at reduced dose)

Question 8

MAC 2nd ppx 1 or 1 + 1 +/- 1

Answer 8

Clarithromycin or azithro + ethambutol +/- rifampin/rifabutin (at same doses as tx)

Question 9

PCP 2nd ppx 1 or 1 or 1 + 1 or 1 or 1

Answer 9

TMP/SMX or dapsone or (dapsone + pyrimethamine) or atovaquone or inhaled pentamidine

Question 10

Toxoplasmosis meningoenchepalitis 2nd ppx 1 + 1

Answer 10

Pyrimethamine + sulfadiazine