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Pharm- Anti Histamines > 1st Generation AntiHistamines > Flashcards

1st Generation AntiHistamines Flashcards

1
Q

Diphenhydramine brand name

A

Benadryl

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2
Q

Diphenydramine Indication

A

Relief of allergic Symptoms caused

by : Anaphylaxis, Sesonal Allerigic rhinitis, Allergic dermatoes

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3
Q

Diphenydramine

Action

A

Antagonizes the effects of histamine at the H1-Receptor

Does not bind to or inactiviate histamine

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4
Q

Diphenydramine

Side Effects/ Adverse

A

Drowsiness, Dizziness, Blurred vision, Hypotention, dry mouth, dry eyes, constipation, Dysuira ( urinary output disfunction), photosensitivity, wheezing

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5
Q

Diphenydramine

contraindiction

A
  • Hypersensitivity , Acute attacks of asthma,COPD, severe liver disease
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6
Q

Diphenydramine

Nursing Consideration

A
  • asses for signs of dysuria, retention, altered frequency,

- Asses cardiac and respriatory sounds

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7
Q

Diphenydramine

Patient teaching

A
  • Avoid driving / operating machineary ( medicine can cause drowsiness)
  • Avoid Alcohol & other CNS Depressants
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8
Q

Brompheniramine Tannate Indication

A

Combination Drug of Antihistamine & Decongestants.

- for allergic rhinitis ,common cold.

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9
Q

Brompheniramine Tannate Action

A

antagonist of the H1 histamine receptors

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10
Q

Brompheniamine Tannate Side Effects/ Adverse Side effects

A

Drowsiness, Dry mouth, Constipation , urinary rentention, insomina, nervousness

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11
Q

Brompheniamine Tannate Contraindiction

A

Angle-closure glacoma, High blood pressure

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12
Q

Brompheniamine Tannate Nursing consideration

A
  • check for urinary rentention
  • monitory signs for hypersenitivity
  • access heart rate
  • Access ECG
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13
Q

Bromopheniamine Tannate Patient teaching

A

Advise patient about the risk of daytime drowsiness and decreased attention and mental focus.

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14
Q

chlorpheniramine Indication

A

Relief of allergic symptoms caused by histamine release, including Nasal allergies, Allergic dermatoses.

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15
Q

Chlorpheniramine

Action

A

Antagonizes the effects of histamine at H2 receptor sites; does not bind to or inactivate histamine.

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16
Q

Chlorpheniramine

Side affects / Adverse effects

A

drowsiness, dizziness, excitation (in children). blurred vision. hypertension, arrhythmias, hypotension, palpitations. dry mouth, constipation, obstruction. retention, urinary hesitancy.

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17
Q

Chlorpheniramine

Contraindication

A

-Closed Angle Glacuma, High blood pressure

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18
Q

Chlorpheniramine

patient teaching

A

Advise patient about the risk of daytime drowsiness and decreased attention and mental focus.

19
Q

Clemastine indication

A

Relief of allergic symptoms caused by histamine release, including Allergic rhinitis, Urticaria.

20
Q

Clemastine Action

A

Antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamin

21
Q

Clemastine Side Effects

A

drowsiness, confusion, dizziness, paradoxical excitation (children). EENT: blurred vision. CV: hypertension, arrhythmias, hypotension, palpitations, tachycardia. GI: dry mouth, constipation, nausea, obstruction, vomiting. GU: urinary retention. Derm: rash. Resp: thick mucus.

22
Q

Clemastine contraindiction

A

Asthma, COPD, Closed Angle Glaucoma, Cardiac Disease

23
Q

Clemastine Nursing consideration

A

Monitor for drowsiness, poor coordination, or dizziness, especially in the older adult or debilitated. Supervision of ambulation may be warranted. Assess for symptomatic relief with use of the medication

24
Q

Clemastine Patient Teaching

A
  • Advise patient about the risk of daytime drowsiness and decreased attention and mental focus.
  • ## Advise patient to avoid alcohol and other CNS depressants because of the increased risk of sedation and adverse effects.
25
Q

Cyproheptadine Brand name

A

Periactin

26
Q

Cyproheptadine Indication

A

Relief of allergic symptoms caused by histamine release including Seasonal and perennial allergic rhinitis; Chronic urticaria, Cold urticaria

27
Q

Cyproheptadine Action

A

Antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamine. Also blocks the effects of serotonin, which may result in increased appetite.

28
Q

cyproheptadine

Side effects

A

drowsiness, excitation (increased in children). EENT: blurred vision. CV: arrhythmias, hypotension, palpitations. GI: dry mouth, constipation. GU: hesitancy, retention. Derm: photosensitivity, rashes. Misc: weight gain.

29
Q

Cyrproheptadine

Contradictions

A
  • Overactive Thyorid Hormone

- High B.P

30
Q

Cyrproheptadine

Nursing Consideration

A

Assess exercise tolerance frequently (BP, heart rate, fatigue levels), and terminate exercise

31
Q

Cyropheptadine

Patient Teaching

A
  • risk of daytime drowsiness and decreased attention and mental focus
  • Advise patient to avoid alcohol and other CNS depressants because of the increased risk of sedation and adverse effects.
  • instruct patient to report other troublesome side effects such as severe or prolonged skin rash, blurred vision, problems with urination, or GI problems
32
Q

Levocetrizine

Brand name

A

Xyzal

33
Q

Levocetrizine

Indication

A

Management of seasonal/perennial allergic rhinitis. Management of chronic idiopathic urticaria.

34
Q

Levocetrizine

Action

A

Antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamine

35
Q

Levocetrizine Side effects / Adverse

A

drowsiness, fatigue, weakness. dry mouth

36
Q

Levocetrizine Contraindiction

A
  • Hypersenstvity

- End stage Renal Disease

37
Q

Levocetrizine

Nursing Consideration

A

guard against falls and trauma (hip fractures, head injury, and so forth). Implement fall-prevention strategies , especially in older adults or patients with excessive drowsiness, weakness, or fatigue

38
Q

Levocetrizine

Patient Teaching

A
  • Day time drowsiness
  • Mindful of dry mouth
  • Avoid CNS depressants & Alcohol
39
Q

Azelastine

Indication

A

Management of the symptoms of seasonal allergic rhinitis in patients ≥5 yr. Management of vasomotor rhinitis in patients ≥12 yr.

40
Q

Azelastine

Action

A

Locally antagonizes the effects of histamine at H1 receptor sites; does not bind to or inactivate histamine

41
Q

Azelastine Side effects / adverse

A

drowsiness, dizziness, dysesthesia, fatigue, headache. epistaxis, nasal burning, pharyngitis, sinusitis, sneezing. bitter taste, dry mouth, nausea. weight gain. myalgia

42
Q

Azelastine Contraindication

A
  • Active & Inactive T.B
  • ## Herpes simplex infection of the eye
43
Q

Azelastine

Nursing Considerations

A
  • Assess dizziness and drowsiness that might affect gait, balance, and other functional activities
  • Assess any muscle pain to rule out musculoskeletal pathology
44
Q

Azelastine

Patient teaching

A
  • day time drowsiness

- Avoid CNS depressants & Alcohol

Pharm- Anti Histamines (2 decks)

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