1_Dermoscopy_Pt 1 Flashcards
what are the layers of the skin?
epidermis, dermis, subcutaneous tissue
what are the layers of the EPIDERMIS?
- Basal (stratum germinativum) – deepest layer
- Prickle (stratum spinosum)
- Granular (stratum granulosum)
- Stratum lucidum** (**ONLY IN PALMS AND SOLES**) **(*KNOW FOR EXAM, “always a good test question”)
- Horny (stratum corneum) – most superficial layer
where in the body is STRATUM LUCIDUM found?
This layer of the epidermis is ONLY FOUND in the PALMS AND SOLES
what are the functions of the skin?
- cold/ heat/ radiation
- pressure/ blows/ abrasion
- action of chemical substances
- invasion by microorganisms
- heat & water loss
- defense against invading microorganisms
- absorption of certain substances
- perspiration
- circ and therm regulation (via derm vasc system)
- pressure/vibration/touch/pain/temp sensory organs
what is another name for the basement membrane?
why is it an area of research interest?
- Dermal-epidermal interface (basement membrane)
- area of research interest bc pathology here can cause visible skin disease
what is the anatomy of the DERMIS layer?
which sublayer has more collagen?
- Separated into _papillary and reticular l_ayer
- **the RETICULAR layer has a lot of collagen
- Place where hair and glands begin
what are the FUNCTIONS of the DERMIS layer?
- Temperature regulation through control of cutaneous blood flow and sweating
- Mechanical protection of underlying structures
which skin layer: consists of spongy connective tissue with energy-storing adipocytes
Subcutaneous or Subcutis layer:
- Consists of spongy connective tissue with energy-storing adipocytes (fat cells)
(T/F) The fat content of the subcutis is the same in all body regions and individuals.
- The fat content of the subcutis is NOT the same in all body regions and DIFFERS in men and women
- Zero fat in and around nail tissue
what is the fat content in and around the nail tissue?
- Zero fat in and around nail tissue
when in development does nail begin to develop?
between 10th-17th week in utero
is when the nail begins to develop
which cells make up the nail plate?
- Onychocytes: one of the tightly packed keratinized cells arranged in layers to make up the nail plate.
what is the nail plate comprised of, in general terms?
the nail plate is formed by mostly nail matrix – w/ some contribution from nail bed, shape contributed from matrix and phalanx
what is directly deep to the nail plate?
distal phalanx directly underneath nail plate;
there is NO SUBCUTANEOUS tissue
compare hair and nails w/ regards to:
- growth
- keratin content
- function
- assoc glands
- where
what are the key differences between APOCRINE and ECCRINE glands of the skin?
what is a sebaceous gland?
- Apocrine gland associated with hair follicle;
- aka Pilosebaceous unit
which glands are where ACNE occurs?
what causes these glands?
- Sebaceous glands are where acne occurs
- Sebaceous glands are caused by metabolic, environmental, etc factors
- can become colonized and then infected
which glands produce sebum?
what is the normal rate, and what decreases the rate?
- sebaceous glands produce sebum
- normal amount is 1mg/10cm2 every 3 hours
- Skin is dry if produces less than that amount
how long does it take for keratinocyte to pass from basal to corneal layer?
8-10 weeks for epidermal cell turnbover
describe the process of epidermal cell turnover
- Keratinocytes divide in basal cell layer, differentiate, and progress upwards to the stratum corneum (no nuclei in corneum)
- No cell division detected past the basal layer
where is no cell division detected past WHICH SKIN LAYER?
No cell division detected past the BASAL layer
what are the big 3 of the skin exam?
ASK
LOOK
PALPATE
What are examples of questions to ASK the patient when preventing for a skin exam?
FIRST, NLDOCAT
- Evolution (How did it begin? How did it change?)
- Involution (How did it go away?)
- What other body parts affected
-
History of rashes/skin cancer
- Topical med history (OTC/Rx/Folk/Home, failure or success?)
- Have you seen a dermatologist?
- Have you had a biopsy?
what factors should you consider when VISUAL AND TOUCH assessment?
(LOOK AND PALPATE)
- Distribution/location (where on the body?)
- Grouping/configuration
- Shape (primary or secondary lesions)
- Size (cm)
- Color (red, blue/cyanotic, pale)
- Temperature (use backs of hands/fingers to determine if cool or warm)
- Mobility (does it lift up?) and turgor (the speed to which it returns to normal)
- Nails
- The skin around the lesions (especially with wounds)
- Moist or dry (wetness or flakes?)
- CHECK THE HANDS!!!