1900-1929

Question 1

1900

Answer 1

PAUL EHRLICH
Antibody formation theory

KARL LANDSTEINER
Discovery of the ABO blood group

Question 2

1902

Answer 2

PORTIER AND CHARLES RICHET
Immediate-hypersensitivity anaphylaxis

Question 3

1903

Answer 3

ARTHUS
Arthus reaction of hypersensitivity

ALMOTH WRIGHT, STEPHEN DOUGLAS, JOSEPH DENYS
Discovered opsonins and describe its relation to phagocytosis

GEORGE SNELL
Worked out the genetics of the murins major histocompatibility complex and generated the congenic strains needed for its biologic analysis

Question 4

1906

Answer 4

VON PIRQUET AND SCHICK
Describe the relation of immunity and hypersensitivity

JEAN DAUSSEL
Early pioneer in the study of MHC or HLA

Question 5

1911

Answer 5

NIEL JERNE
Developed hemolytic plaque assay and an early version of clonel selection

Question 6

1915-1987

Answer 6

PETER MEDAWAR
Made studies on acquired immunologic tolerance

Question 7

1920

Answer 7

JULES BORDET
Received nobel price for works on complement

BARUJ BENACERRAF
Discovered immune response genes

Question 8

1920-1985

Answer 8

RODNEY PORTER
Polypeptide structure (Y-SHAPE)

Question 9

1921

Answer 9

ALBERT CALMETTE AND CAMMILE GUERIN
1st successful tuberculosis vaccine

ROSALYN YALOW
Developed RIA of peptide hormones

Question 10

1922

Answer 10

ALEXANDER FLAMMING
Described lysozyme action

Question 11

1924

Answer 11

JAMES GOWAN
Disovered that adaptive immunity is mediated by lymphocytes

Question 12

1927

Answer 12

CESAR MILSTEIN AND GEORGES KOHLER
Developed monoclonal antibody formation

Question 13

1930

Answer 13

GERALD EDELMAN
First complete sequence of Ab molecule