19 Arterial Occlusion Flashcards

1
Q

Most important risk factors for peripheral arterial disease

A

Smoking
Diabetes

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2
Q

Most frequently diseased arteries leading to limb ischemia (in order of occurence)

A
  1. Femoropopliteal
  2. Tibial
  3. Aortoiliac
  4. Brachiocephalic vessels
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3
Q

Number of hours before peripheral nerves and skeletal muscle suffer irreversible changes

A

4 to 6 hours

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4
Q

Six Ps of acute limb ischemia

A

Pain
Pallor
Pulselessness
Paralysis
Paresthesias
Poikothermia

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5
Q

Cutoff time perior for “acute limb ischemia”

A

2 weeks

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6
Q

Define Rutherford Criteria I (Viable)

A

Sensory loss: none
Muscle weakness: none
Audible doppler signals

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7
Q

72/M came in as a case of ALI. Upon PE, noted with sensory loss of the entire dorsum of the feet, with moderate muscle weakness. Doppler studies showed inaudible arterial signals but with audible venous signal. What is the rutherford criteria?

A

Rutherford II (Threatened), type B (Immediately threatened)

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8
Q

Define Rutherford criteria II (Threatened), type B

A

Sensory loss: more than toes, associated with rest pain
Muscle weakness: mild to moderate
Doppler studies:
Arterial - inaudible
Venous - audible

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9
Q

Define Rutherford Criteria II, Marginally threatened (type A)

A

Sensory loss: minimal (toes) or none
Muscle weakness: none
Inaudible arterial signals
Audible venous signals

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10
Q

Rutherford Criteria III (Irreversible) definition

A

Sensory loss: profound; anesthetic
Muscle weakness: paralysis profound
Inaudible ARTERIAL AND VENOUS

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11
Q

Definition of claudication

A

Cramp-like pain, ache, or tiredness that is brought on by exercise and relieved by rest (same with angina in the heart)

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12
Q

Difference of claudication and acute limb ischemia

A

Pain of ALI is not relieved with rest, not well localized and can present as marked worsening of chronic pain

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13
Q

How do you measure Ankle-Brachial Index?

A

Ratio of systolic blood pressure with the cuff just above the malleolus to the highest brachial pressure in either arm

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14
Q

Cut-off ABI in patients with CHRONIC peripheral arterial disease?

A

<0.9

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15
Q

Cut off Ankle Brachial Index value for severe disease?

A

<0.4

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16
Q

Treatment of ALI in the ED:

A
  1. IV unfractionated heparin (weight based 80u/kg bolus followed by infusion of 18u/kg/h)
  2. Antiplatelet therapy: aspirin 325mg PO first dose OR clopidogrel 75mg if with allergies to aspirin
17
Q

Stratifying patients with ALI by Rutherford criteria with early surgical consultation guides initial care. What is the treatment plan for each stage?

A

Stage I and IIa: diagnostic imaging to more definitive treatments
Stage IIb: immediate revascularization WITHOUT diagnostic imaging
Stage III: amputation

18
Q

Class I recommendation treatment for intermittent claudication

A

Cilostazol