18: Diagnostic Adjuncts to COE

Question 1

Known high risk sites for oral SCC

Answer 1

1. ventrolateral tongue
2. FOM
3. anterior tonsillar pillars/retromolar area

Question 2

High-risk physical features

Answer 2

1. Large (>1cm) non-homogenous white patches or plaques (irregular leukoplakia).
2. Mixed red/white lesions (erythroleukoplakia)
3. Erythroplakia, persistent ulceration, pain, induration

Question 3

Timing for follow-up of suspicious oral lesions

Answer 3

Initial: 7-21 days, +/- conservative therapy
If no progression: 1, 3, 6, 12 months
If worsening, biopsy

Question 4

Mechanism of ViziLite Plus

Answer 4

Disposable, chemiluminescent light source and holder.

Uses 1% acetic acid solution, TBlue (toluidine)

Question 5

Results of ViziLite Plus

Answer 5

Infrequent correlation with biopsy

Common distractors

Question 6

Disposable, chemiluminescent light source and holder.

Answer 6

ViziLite Plus

Question 7

Uses 1% acetic acid solution

Answer 7

ViziLite Plus

Question 8

Uses TBlue (toluidine)

Answer 8

ViziLite Plus

Question 9

Mechanism of VELscope

Answer 9

Visually Enhanced Lesion Scope

Based on tissue fluorescence

Question 10

Results of VELscope

Answer 10

Good: Margin analysis
Limitations: distractions, false positives/negatives

Question 11

Based on tissue fluorescence

Answer 11

VELscope

Question 12

Good for margin analysis

Answer 12

VELscope

Question 13

Mechanism of Identafi 3000 Ultra

Answer 13

Based on multi-spectral fluorescence and reflectance spectroscopy

1. White for exam
2. Violet for tissue fluorescence
3. Amber for abnormalities (observe reflectance, vasculature)

Question 14

Uses 3 colors sequentially

Answer 14

Identafi 3000 Ultra

Question 15

ESPyOC

Answer 15

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