✅17 - Inherited Change Flashcards

1
Q

What is a genotype?

A

The genetic makeup of an organism, all the alleles that it has

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2
Q

What is a phenotype?

A

The observable or biochemical characteristics of an organism. The result of the interactions between expression of the genotype and the environment

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3
Q

What is a gene?

A

A length of DNA

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4
Q

What are alleles?

A

Different forms of genes

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5
Q

What is a locus?

A

The position of a gene on a particular DNA molecule

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6
Q

What are homologous pairs of chromosomes?

A

Pairs of chromosomes with approximately the same length, gene position and centromere location

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7
Q

What is homozygous?

A

When an individual has two of the same allele

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8
Q

What is heterozygous?

A

When an individual has two different alleles

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9
Q

What does codominant mean?

A

Where two alleles both contribute to the phenotype

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10
Q

What are multiple alleles?

A

When a gene has more than two allelic forms, of which only two may be present at the loci on an individual’s homologus chromosomes

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11
Q

What is monohybrid inheritance?

A

Inheritance of a single gene

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12
Q

What is the F1 generation?

A

First filial - two different pure breed organisms crossed to give hybrid offspring

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13
Q

What is the F2 generation?

A

Second filial - heterozygous offspring from F1 generation crossed together to produce more offspring

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14
Q

What is the law of segregation?

A

In diploid organisms, characteristics are determined by alleles that occur in pairs. Only one of each pair of alleles can be present in a single gamete.

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15
Q

Why are actual results of genetic crosses rarely the same as predicted?

A

Due to statistical error

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16
Q

How can results of genetic crosses be made to be closer to predicted ones?

A

By using a very large, representative sample

17
Q

What is dihybrid inheritance?

A

Two characteristics, determined by two different genes located on different chromosomes are inherited

18
Q

What is the law of independent assortment?

A

Each member of a pair of alleles may combine randomly with either of another pair

19
Q

What is an example of codominance?

A

The snapdragon plant, which has one allele for an ezyme that catalyses the formation of red pigment and one which produces no pigment - red and white. However, the two colour combine to give pink flowers

20
Q

What is an example of multiple alleles?

A

Blood group

21
Q

Which sex chromosomes do females have?

22
Q

Which sex chromosomes do males have?

23
Q

How many different types of gamete do males produce?

A

2, one X and one Y

24
Q

What are sex-linked genes?

A

Any gene carried on wither the X or Y chromosome

25
Why can some genes be more prevalent in males than females?
The X chromosome is much longer than the Y, so more most of the X chromosome, there is no homologous equivalent and those recessive characteristics on the X chromosome will be more frequent in males
26
What is an X-linked genetic disorder?
A disorder caused by a defective gene on the X crhomosome
27
What is an example of an X-linked genetic disorder?
Haemophillia
28
What are autosomes?
Any chromosome which is not a sex chromosome
29
What is autosomal linkage?
When two or more genes are carried on the same autosome
30
Why do linked genes remain together when passed onto offspring?
Because, assuming that there is no crossing over, they do not segregate in accordance with Mendel's law of independent assortment
31
What is epistasis?
When the allele of one gene affects or masks the expression of another in the phenotype
32
What is an example of epistasis?
In mice, where several genes determine coat colour
33
How does epistasis in mice work?
Gene A controls distribution of black pigment and whether they are banded or not. The dominant allele of A leads to hairs with black bands, which recessive a produces uniform black hairs. Gene B controls expression of A. Dominant B leads to production of the pigment while recessive b leads to no pigment
34
Which statistical test is used for genetics?
Chi Squared