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17 - 1 Flashcards

1
Q

Which drug is bactericidal?

A

Metronidazole

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2
Q

Which drug is an antineoplastic?

A

Cytarabine

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3
Q

Pulmonary fibrosis?

A

Bleomycin

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4
Q

Cardiotoxicity?

A

Doxorubicin (Anthracyclines)

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5
Q

Peripheral neuropathy side effect?

A

Vincristine (vinca alkaloid)

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6
Q

MOA of vinca alkaloids?

A

Suppress microtubule polymerization

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7
Q

What drug has beta-lactamase resistance due to clavulanic acid? Augmentin

A

Augmentin

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8
Q

What bacteria is responsible for periodontal abscesses?

A

Bacteriodes

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9
Q

Amoxicillin and augmentin are responsible for what side effect?

A

Diarrhea

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10
Q

What antibiotic commonly causes overgrowth of clostridium difficile?

A

Clindamycin

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11
Q

Which antibiotic commonly has drug-drug interactions?

A

Erythromycin??

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12
Q

Which of the following is bactericidal?

A

Metronidazole

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13
Q

Which of the following does not have a drug complication with Warfarin?

A

Amox (metron does)

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14
Q

What systemic antibiotic would you use for an already immunosuppressed patient? ??

A

bactrim
or amox

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15
Q

What drug is know to cause immunosuppression?

A

Methotrexate

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16
Q

Why do we only prescribe Azithromycin for short periods of time?

A

Long half-life

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17
Q

What causes tooth discoloration in children?

A

Doxocycline

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18
Q

Which of the following drugs in condraindicated for use during pregnancy?

A

Doxocycline

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19
Q

Which of the following has a mechanism of action that acts directly on ergosterol?

A

Nystatin

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20
Q

Which would sufficiently treat against bacteria producing beta lactamase?

A

Amoxicillin +
Clavulanic acid

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21
Q

Generalized aggressive periodontitis. What would be the most appropriate adjunctive ABX
regimen?

A

Amox + metronidazole

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22
Q

What ABX best treats a purulent abscess?

A

TMP/SMX?? (clinda or augmentin?)

23
Q

Which of the following of the backbone of HAART?

A

NRTI (nucleoside reverse transcriptase
inhibitor)

24
Q

Which prohibits the assembly of new retroviral cells?

A

PI’s (protease inhibitors) “navirs-ritonavir)

25
Q

Antibiotic prophylaxis when?

A

Prosthetic heart valve

26
Q

What procedure would be consider high risk for infective endocarditis?

A

Manipulation of gingiva

27
Q

Which of the following is not a life-long infection?

A

Influenza A

28
Q

Which would be the treatment of influenza? Oseltamavir (Tamiflu)

A

Oseltamavir (Tamiflu)

29
Q

Which would be the acute treatment for cryptococcal mengingitis?

A

Amphotericin B

30
Q

What ABX would you use to treat an early odontogenic infection (<3 days)?

A

Penicillin

31
Q

MOA of fluconazole is what?

A

To prevent conversion of lanosterol to ergosterol

32
Q

Which drug causes periostitis after chronic use?

A

Voriconazole

33
Q

Adverse lipid effects?

A

Protease Inhibitors (PI’s)

34
Q

What agent should be used for an HIV patient when the CD4 count drops below 200?

A

Bactrim

35
Q

Ritonavir?

A

Is a protease inhibitor??

36
Q

What ABX acts on the bacterial cell wall?

A

Amoxicillin (penicillin, etc… Beta lactams)

37
Q

Which of the following scenarios suggests need for adjunctive systemic ABX in a patient with
periodontal abscess?

A

Fever

38
Q

All patients with a reported heart condition should receive antibiotic prophylaxis prior to a
dental procedure?

A

False

39
Q

What group of pathogens is most common for late odontogenic infections?

A

Strict anaerobes

40
Q

Which of the following most accurately described a bacterial sinus infection?

A

Purulent nasal drainage and facial pain with no improvement after 10 days

41
Q

The more time an antifungal agent remains in the mouth, the more effective the agent will be
when treating oropharyngeal candidiasis?

A

True (because of time dependent)

42
Q

Which group of antiretrovirals is most likely to cause metabolic side effects?

A

PI’s (protease
inhibitors)

43
Q

Which of the following options for oropharyngeal candidiasis has the highest cariogenic risk?

A

Nystatin

44
Q

What is the first step of Post Exposure Prophylaxis?

A

Cleanse

45
Q

Which of the following is an appropriate definition for Beta-Lactamase?

A

An enzyme released
from a bacteria that has the potential to disable an antibiotic

46
Q

The cephalosporin class of antibiotics kills anaerobic bacteria?

A

False

47
Q

Metronidazole (Flagyl) eradicates anaerobic bacteria?

A

True

48
Q

Which of the following drugs acts directly on cell wall formation?

A

Amox

49
Q

Which of the following antibiotics is associated with tendon side effects?

A

Ciprofloxacin
(fluoroquinolones)

50
Q

Which of the following is metabolized into a toxic metabolite that causes hemorrhagic cystitis?

A

Cyclophosphamide

51
Q

How do you alleviate the symptoms of the toxic metabolite acrolein?

A

MESNA

52
Q

Which of the following best describes how a mutated tumor suppressor gene may lead to the
generation of cancer cells?

A

Inhibitory proteins may not function properly and inappropriate
growth of cells remains unchecked

53
Q

Paclitaxel inhibits mitosis of cancer cells by

A

inhibiting disassembly of microtubulin (taxanes)

54
Q

Peripheral neuropathy is a notable side effect of which of the following antineoplastic agents?

A

Oxaliplatin and vincristine

Farm (3 decks)

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