16.2 Physiology- Kidney function 2 Flashcards
What substance gets secreted?
K+
What substance gets completely excreted?
What doesn’t get excreted at all?
Creatinine
Glucose
What is the difference between excretion and renal clearance?
Excretion of W: U concentration of W x U volume (UV)
Renal clearance of W: excretion/plasma concentration of W (UV/P)
What is the clearance of a substance (X) defined as?
Volume of plasma cleared of X per time
What does inulin clearance determine? What is it usually?
GFR, 100mL/min
What is the glucose clearance? What happens if it is not at this normal rate?
0mL/min in a healthy individual
Hyperglycaemia likely (overload of reabsorption mechanism)
What is the penicillin clearance rate? What does this mean?
150mL/min (more than GFR!)
No reabsorption occurs