1.6 - cell division Flashcards
Outline the structures of a chromosome
long, thin structure of DNA.
-2 sister chromatids held together at the centromere
How many pairs of chromosomes do humans have?
23 homologous pairs
diploid
2n
Describe interphase
-longest division of cell cycle
-DNA doubles
Organelles replicate
-proteins are synthesised
-active process , requires ATP
Prophase
-Chromatids condense + become visible
-nuclear envelope disintegrates
-centrioles move to opposite poles
-nucleolous disappears
-spindle fibres form
Metaphase
The chromosomes align themselves along the equator
-centromere attaches to spindle fibres
Anaphase
-Spindle fibres begin to contract
-centromeres separate -chromatids move to opposite poles
Telophase
- chromatids reach poles and referred to as chromosomes again
-chromasomes disperse and lengthen - nuclear envelope redevelops
- nucleolus reforms
-spindle fibres break down
Cytokenesis
in animals vs plants
-splitting of the cytoplasm to form two new cells
ANIMALS - constriction of the parent cell around the equator. Cleavage furrow
PLANTS - cell plate form across equator, they extend to form new cell
Where does mitosis occur in plants and animals ?
- animals = bone marrow, tissue, muscle tissue
-plants- meristems
What is the significance of Mitosis?
- Growth and repair
-Aesexual reproduction
-red and white blood cell production
-increase in call number in plants
Define Proto-oncogene
A gene that controls mitosis, before it is exposed to radiation
Oncogene
A gene wich causes uncontrolled cell division
Meiosis
A two staged cell division which creates 4 haploid cells.
difference between meiosis 1 and 2
Meiosis 1= bivalente chromosomes separate
meiosis 2 = chromatids separate
Meiosis 1 = corssing over, meiosis 2 has no crossing over.
Prophase 1
-Chromatids condense and are in bivalent pairs.
-joined at the chiasmata where crossing over occurs
-intorduces genetic variation
-genes are swapped between chromosomes.