151 - adrenal cortex path Flashcards
where do glucocorticoids, mineralocorticoids, and and androgens get made in the adrenal cortex?
zona fasciculata, zona glomerulosa, zona reticularis
what are symptoms of adrenal hypofunction?
weakness, hypotension, pigmentation, hypoglycemia, hyperkalemia, hyponatremia
describe 21-hydroxylase deficinecy and 11-hydroxylase deficiency
21 deficiency causes salt loss and viralization due to to cortisol and aldosterone deficiency but accumulation of androgen precursors. 11 deficiency causes salt retention and viralization due to cortisol loss and accumulation of 11-deoxycorticosterone and androgen
what are the effects of mineralocorticoids?
sodium retention, potassium excretion, acid excretion