151 - adrenal cortex path Flashcards

1
Q

where do glucocorticoids, mineralocorticoids, and and androgens get made in the adrenal cortex?

A

zona fasciculata, zona glomerulosa, zona reticularis

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2
Q

what are symptoms of adrenal hypofunction?

A

weakness, hypotension, pigmentation, hypoglycemia, hyperkalemia, hyponatremia

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3
Q

describe 21-hydroxylase deficinecy and 11-hydroxylase deficiency

A

21 deficiency causes salt loss and viralization due to to cortisol and aldosterone deficiency but accumulation of androgen precursors. 11 deficiency causes salt retention and viralization due to cortisol loss and accumulation of 11-deoxycorticosterone and androgen

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4
Q

what are the effects of mineralocorticoids?

A

sodium retention, potassium excretion, acid excretion

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