15. Protozoa Flashcards

1
Q

What is a protozoa?

A

a single celled organism with nuclei

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2
Q

what does Protozoa mean?

A

first animal

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3
Q

what kingdom is Protozoa part of?

A

Protists

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4
Q

what does the kingdom Protista include?

A

single-celled organisms, including the Dinoflagellates, and the single celled algae

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5
Q

in general, do Protozoans photosynthesize?

A

no

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6
Q

are Protozoans generallt motile?

A

yes

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7
Q

where can protozoans live in the body?

A

in all parts of the body, including the gut, mouth, skin, blood, live, spleen, genital tract, lungs brain and heart

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8
Q

what are the different groups of Protozoa, of which parasitize humans?

A

Amoeba

Flagellates

Ciliates

Sporozoa

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9
Q

what Protozoan group is Entamoeba in?

A

Amoeba

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10
Q

what Protozoan group are Giardia, Trichonomas, Trypanosoma and Leishmania in?

A

Flagellates

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11
Q

do protozoa have rigid cell walls?

A

no

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12
Q

how do protozoa digest their food?

A

in vacuoles

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13
Q

how do protozoa gain entry to a host?

A

orally or through the bite of a blood-sucking vector

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14
Q

T/F

From the point of view of functional and physiological

complexity, a protozoan is more like an animal than like

a single cell.

A

True

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15
Q

define niche selection

A

selected to live in a specific essential niche

defined by anatomical, physiological and biochemical

features of the site

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16
Q

what is pathogenesis related to?

A

the niche, the metabolic requirements of the parasite and the population density

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17
Q

what are some ways that protozoa will feed/ingest nutrients?

A

active transport, phagocytosis, or pinocytosis

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18
Q

where does digestion take place in protozoa?

A

in a vacuole through lysosomal enzymes

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19
Q

how is waste excreted in protozoa?

A

by diffusion or exocytosis

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20
Q

what protozoan group is Balantidium coli in?

A

ciliates

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21
Q

how do amoebas move?

A

pseudopodia

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22
Q

how do flagellates and ciliates move?

A

cilia and flagella

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23
Q

how are cilia and flagella microtubules arranged?

A

9+2

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24
Q

how do protozoa reproduce asexually?

A

binary fission

multiple fission

budding

i.e. variations of mitotic division

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25
how do protozoa reproduce sexually?
gamete fusion conjugation
26
what is schozogony?
multiple fission
27
describe binary fission
mitosis leads to the cell splitting yielding two daughter cells
28
describe multiple fission
nucleus undergoes multiple divisions before the cell divides - gives rise to multiple daughter cells
29
which protozoa are more likely to reproduce sexually, through gamete fusion?
the ones with an insect vector phase
30
define trophozoite
any stage in a protozoan’s life cycle which can ingest nutrients. In practice it refers to the motile form (pseudopods, cilia, flagella)
31
define cyst
Non‐motile form, protected by a membrane. Often the \*infective stage\*
32
define excystation
process of emergence of the trophozoite from the cyst
33
what disease does *Giardia intestinalis* cause?
giardiasis
34
where is giardiasis acquired?
contaminated water
35
what disease does *Trichonomas vaginalis* cause?
vaginosis
36
what disease does *Trypanosoma brucei gambiense* cause?
african sleeping sickness
37
what disease does *Entamoeba histolytica* cause?
Amoebic dyentery
38
how is african sleeping sickness transmitted?
the tsetse fly
39
what disease does *Tripanosoma cruzi* cause?
chagas disease
40
how is *T. cruzi* transmitted?
the kissing bug
41
what disease does *Leishmania* spp. cause?
leishmaniasis
42
how is leishmaniasis transmitted?
sand flies
43
what is the phylum of *Entamoeba histolytica*?
Sarcodina
44
who is in the phylum Mastigophora?
*Giardia intestinalis, Trichomonas vaginalis, , Trypanosoma brucei gambiense, Trypanosoma cruzi, and Leishmania?*
45
what disease does *Balantidium coli* cause?
Balantidial dyentery
46
how is *B. coli* contracted?
contaminated water
47
what phylum is *B. coli* in?
Ciliata
48
what disease does *Plasmodium* spp. cause?
malaria
49
how is *Plasmodium* spp. transmitted?
Anopheles mosquito
50
what phylum is *Plasmodium* spp. in?
Sporozoa (apicomplexans)
51
what disease does *Toxoplasma gondii* cause?
toxoplasmosis
52
what phylum is *Toxo* in?
Sporozoa (apicomplexans)
53
how can *Toxo* be contracted?
raw meat, cat feces
54
what disease does *Cryptosporidium* cause?
Diarrhea
55
what phylum is *Cryptosporidium* in?
Sporozoa (apicomplexams)
56
how is *Cryptosporodium* spread?
humans, animals
57
What is this?
Malaria - *Plasmodium* spp.
58
What is this?
Toxoplasmosis *(Toxoplasma gondii)*
59
What is this?
Criptosporidiosis - *Cryptosporidium parum*
60
What are the symptoms of *Toxo?*
Does not cause symptoms in most people. Can cause fatalities in unborn children and in AIDS patients.
61
how can *Toxo* be prevented?
Thoroughly cook all meats, be careful handling cat litter, feed cats commercial cat food, cover sand boxes when not in use and wash all fruits and vegetables before eating.
62
what are the symptoms of *Plasmodium* spp.?
fever, headache and vomiting, can be fatal
63
how can *Plasmodium* spp. be prevented?
Spread by mosquito bites. The use of DDT in the U.S. and many other countries brought malaria under control. It is still a problem in many developing countries.
64
what are the symptoms of *C. parvum?*
Diarrhea. May also cause vomiting, headache, fever and stomach cramps. Can be fatal to those in poor health.
65
how can *C. parvum* be prevented?
Use an approved water filter, an approved brand of bottled water or boil water for 1 minute. Avoid drinking water from lakes and rivers.
66
T/F • Apicomplexa consists of all parasitic species
True
67
do apicomplexa have cilia or flagella?
not usually
68
what is the hallmark of Apicomplexa
apical complex structure
69
what do most Apicomplexa possess
the apicoplast organelle
70
what is the appearance of the apical complex?
An organ complex of the Apicomplexa that appears as a conical structures on the tapered end (or the apical end) of the cell, and contains rhoptries, micronemes, dense granules, polar rings, and a conoid.
71
what is the mechanism of the apical complex?
• Rhoptries, micronemes and dense granules discharge substances into the host cell during the invasion process through a system of ducts which open up at the apical end. • The substances released play a crucial role in destabilizing the host cell membrane and in formation of an invasion pit.
72
name the structures
73
what is the use of the apical complex?
it is involed in penetrating the host
74
how many membranes does the apical complex have?
4
75
why is the apicomplast also known as the plastid?
drugs against chloroplasts and prokaryotes also kill apicomplexan parasites
76
how did the apicomplast likely become encased in four membranes?
via a secondary endosymbiotic event - the promary endosymbiosis gives rise to 2 membranes, and then if that is endocytosed again you will have 4 membranes
77
what is primary endosymbiosis?
the capture of a cyanobacterium by a eukaryotic heterotroph - the cyanobacterium would have modified during evolution to give rise to a plastid with two surrounding membranes
78
what is secondary endosymbiosis?
proposed to be the engulfment of a red algae containing a chloroplast by a eukaryotic heterotroph - the red algae would have become the plastic with four ssurrounding membranes
79
is the apicomplast a chloroplast?
NO
80
do apicomplasts have chloroplasts?
NO they are absent
81
is the apicomplast vital for the pasite's survival?
yes
82
what is the apicomplast possibly involved in?
lipid metabolism
83
if we remove the apicomplast, what is the effect on the parasite?
they will survive but they will not be able to invade new hosts
84