15 Pedigree

Question 1

What does a diamond in a pedigree mean?

Answer 1

unknown

Question 2

What does a number inside a shape on a pedigree mean?

Answer 2

Indicates multiples of offspring in large pedigrees

Question 3

What does a Y shaped connector for offspring indicate?

Answer 3

twins if identical also has a crossbar

Question 4

What are double horizontal lines in pedigree mean?

Answer 4

consanguineous

Question 5

What does a dot in the middle of a symbol mean?

Answer 5

X linked Carrier

Question 6

How does consanguinity affect probability of recessive genes?

Answer 6

The probability of shared genes being passed increases for every generation of offspring that were from consanguineous mating

Question 7

Give the probability of sharing a gene from siblings to third cousins.

Answer 7

half for siblings one eighth for first cousins 1/32 for second cousins and 1/128 for third cousins

Question 8

What are the four characteristics of x-linked dominant pedigrees?

Answer 8

Show how the risk of cystic fibrosis with a normal risk of 1/25 increases in consanguinity with a first cousin., 1/25 times 8 (cousins have 1/8 probability to share a gene) equals 1/3 probability