147. Cardio drugs Flashcards

1
Q

Dysrhytmias associated with dig tox

A
NONSPECIFIC
- PVC
- any degree block
- sinus brady or tachy
- SA block
- Afib with slow
- A tach
- junctional
- AV dissociation
- V tach
- torsades
- v fib
SPECIFIC
- slow afib
- junctional
- atrial tach with block
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2
Q

Non cardiac Sx of dig tox

A
Weakness and fatigue
N/V/D
abdo pain
snowy visions
photophobia
diplopia
HA
dizzy
confusion
hallucination
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3
Q

Differences between acute vs chrinc toxicity

A
Chronic
- higher mortality
- ventricular dysrythmias more
- elderly
underlying heart disease

ACute

  • lower mort
  • brady and AV block more
  • younger
  • no hear disease
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4
Q

Testing for dig tox

A

Levels

- peak 1.5-2 hours

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5
Q

MGMT of dig

A

FAB

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6
Q

8 adult indications for FAB

A
  1. Vent dysrythmias
  2. hemodynamic bradys
  3. K > 5
  4. progressive rhythm problems or rising K
  5. co-ingestion of other cardio drugs
  6. ingestionso plants and dysrhytmias
  7. > 10mg
  8. levels > 6ng/L
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7
Q

Amount of FAB

A

Arrest
- 10 vials
Non-arrest
- 1 vial binds 0.5mg

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8
Q

goals of K in dig tox

A

maintain 3.5-4

if >5, then FAB

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9
Q

other meds of tachy in dig tox

A

phenytoin

FAB still preferred

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10
Q

Most dangerous BB

A

propranolol

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11
Q

3 places Beta acts

A
  1. vasodilation
  2. Liver
  3. Lung
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12
Q

10 Sx of BB tox

A
  1. brady
  2. hypoT
  3. unconscious
  4. resp arrest
  5. hypoglycemia
  6. seizures
  7. bronchospasm
  8. VT or VF
  9. mild hyperK
  10. hepatotox
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13
Q

Dx testing for BB tox

A

ECG

glucose if CNS depression

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14
Q

MGMT of hypoT, brady and AV block in BB tox

A

fluids
atropine trial
pacing

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15
Q

goal of Ca in BB tox

A

final common pathway of B receptro intracellulary

- give 1-2 amps CACl

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16
Q
  1. antidote for BB
A
high dose insulin
- superior to glucagon
- ionotropic effecyt
- monitor K
glucagon
- ionotropic effect and chronotropic
- does not need beta receptor
17
Q

Adjunct meds for BB tox

A
  1. Bicarb
    - until QRS <120
  2. Pressors
    - any one
    - MAP > 60
  3. Intralipip
    - if failing else