14.1 Hormonal Communication Flashcards
What is an endocrine gland?
An endocrine gland is a group of cells which are specialised to secrete hormones.
Has no ducts
What are hormones?
Hormones are chemical messengers which travel around the body in the blood stream.
Which hormones does the pituitary gland produce?
- Growth hormone
- Anti-diuretic hormone
- Gonadotrophins
What is the role of the growth hormone?
controls growth of bones and muscles
What is the role of the anti-diuretic hormone?
The anti-diuretic hormone increases reabsorption of water in the kidneys.
What is the role of gonadotrophins?
Gonadotrophins control the development of ovaries and testes
What hormone does the thyroid gland produce and what is it responsible for?
Thyroxine.
- Controls rate of metabolism
- Controls rate that glucose is used up in respiration
- Promotes growth.
What hormone does the adrenal gland produce and what is it responsible for?
Adrenaline.
- Increases heart and breathing rate
- Raises blood sugar level
What hormone does the testes produce and what is it responsible for?
Testosterone.
- Controls sperm production and secondary sexual characteristic.
What hormone does the pineal gland produce and what is it responsible for?
Melatonin.
- Affects reproductive development and daily cycles.
What hormone does the thymus produce and what is it responsible for?
Thymosin.
- Promotes production and maturation of white blood cells.
What hormone does the pancreas produce and what is it responsible for?
Insulin: Converts excess glucose into glycogen in the liver.
Glucagon: Converts glycogen back to glucose in the liver.
What hormone does the ovary produce and what is it responsible for ?
- Oestrogen: Controls ovulation and secondary sexual characteristics
- Progesterone: Prepares uterus lining for receiving an embryo
How are hormones transported to target cells?
1) The hormones diffuse out of the blood and bind to specific receptors for that hormone, found on the membranes or in the cytoplasm of target cells.
2) Once bound to their receptors the hormones stimulate the target cells to produce a response.
What are steroid hormones?
- Steroid hormones are lipid-soluble.
- They pass through the lipid component of the cell membrane and bind to steroid hormone receptors to form a hormone-receptor complex.
Give an example of steroid hormones.
Oestrogen
What are non-steroid/peptide hormones?
- Non-steroid hormones are hydrophilic so cannot pass directly through the cell membrane,
- Instead they bind to specific receptors on the cell surface membrane of the target cell.
- This triggers a cascade reaction mediated by chemicals called secondary messengers/cAMP
Give examples of non-steroid hormones
Adrenaline
What are the two parts of the adrenal gland?
1) The adrenal cortex
2) The adrenal medulla
What are three main types of hormones produced by the adrenal cortex?
1) Glucocorticoids
2) Mineralocorticoids
3) Androgens
What main hormone is produced from glucocorticoids and what is it responsible for?
Cortisol.
- regulates metabolism of proteins and glucose
- regulates blood pressure and cardiovascular function in response to stress.
What other hormone is produced from glucocorticoids and what is responsible for?
Corticosterone.
- This works with cortisol to regulate immune response and suppress inflammatory reactions.
What main hormone is produced from mineralocorticoids and what is it responsible for?
Aldosterone.
- Helps control blood pressure by maintaining blood pressure between salt and water concentration in the blood and bodily fluids.
What hormones do androgens produce?
Small amounts of male and female sex hormones.
When are the hormones of the adrenal medulla released?
Hormones of the adrenal medulla are released when the sympathetic nervous system is stimulated, and when the body is stressed.
What hormones are secreted by the adrenal medulla?
- Adrenaline
- Noradrenaline
What is the role of adrenaline?
- Adrenaline increases the heart rate sending blood quickly to muscles and brain.
- Rapidly raises blood glucose concentration levels by converting glycogen to glucose in the liver.
What is the role of noradrenaline?
This hormone works with adrenaline in response to stress, producing effects such as:
- Increased heart rate
- Widening of pupils
- Widening of air passages in the lungs
- Narrowing of blood vessels in non-essential organs.