14 Jan 24 Flashcards

1
Q

Spinal epidural abscess causes ?

A

💩Staph aureus
💩Distant infection (cellulitis ,joint/bone)
💩Spinal procedure(epidural catheter)
Direct inoculation
💩Injection drug use
💩 immunocompromised state DM , alcoholic
💩trauma and epidural hematoma (that gets infected )

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2
Q

Spinal Epidural abscess CF

A

➡️Fever (50%)
➡️Focal/severe back pain
➡️Neurologic findings (motor/sensory change, bowel bladder dysfunction,paralysis)

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3
Q

SEA dx

A

🖍⤴️ ESR
🖍Blood and aspirate cultures
🖍MRI OF SPINE with contrast (to see presence and extent of infection that cannot be seen on CT or Xray)

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4
Q

Ttt of SEA

A

🛞Broad spectrum antibiotics (vancomycin plus ceftriaxone)
🛞Aspiration/ surgical decompression

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5
Q

SEA progression ……

A

Progressive symptoms due to compression of spinal cord

Focal back pain
➡️ nerve root pain (shooting , electric-shock sensation)
➡️ motor weakness , sensory changes, bowel / bladder dysregulation
➡️ paralysis

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6
Q

SEA and trauma

A

Trauma can lead to dev of epidural hematoma that may expand and become infected. Leading to abscess.

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7
Q

Cervical spine injury management

A

High risk injury
High mechanism
Trauma causing concomitant closed head injury

Do CT with contrast

Low risk injury
Do NEXUS low risk criteria for cervical spine imaging

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8
Q

NEXUS low risk criteria for cervical spine imaging

A

Any of the following NSAID

🤡Neurologic deficit. N
🤡spinal tenderness S
🤡Altered mental status A
🤡intoxication I
🤡distracting injury D

If none present NO CT scan indicated

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9
Q

Transverse myelitis mechanism

A

Immune mediated infiltration of inflammatory cells in a segment of spinal cord causing oligodendrocyte cell death and demyelination.

Trigger: recent infection
Bimodal peak

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10
Q

Transverse myelitis CF

A

> or equals 1 contiguous spinal cord segment inflammation (mostly thoracic cord) causing rapid progressive myelopathy

➡️ motor weakness progresses from flaccid to spastic paraparesis (UMNS)
➡️autonomic dysfunction
Bowel/bladder incontinence or retention sexual dysfunction
➡️ sensory dysfunction
Pain , paresthesia , numbness with distinct sensory level

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11
Q

Dx of transverse myelitis

A

MRI
Enhaced affected cord segments

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12
Q

Ttt of TM

A

High dose IV steroids

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13
Q

Spinal cord injury managament

A

ABC
Catheterisation (disruption of autonomic fibers)

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14
Q

Tethered cord (spinal dysraphism) CF

A

▶️Back/leg pain worse with activity
▶️Neurologic findings eg weakness , hyporeflexia
▶️New onset scoliosis
▶️Lumbosacral cutaneous abnormailty
(Lipoma)

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15
Q

Tethered cord dx

A

MRI

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16
Q

Tethered cord mechanism

A

Stretch induced dysfunction of spinal cord

In closed spinal dysraphism the posterior arches fail to fuse while overlying skin remains intact
The spinal cord abnormally attaches to surrounding tissues (lipoma) extending from spinal canal to subcut tissues.

As the child grows inferior end of spinal cord remains fixed and stretches rather than rising in spinal canal.
Stretching due to repetitive movements exacerbates cord dysfunction leading to progressive back buttock leg pain.

17
Q

Cervical myelopathy (compression)
Cause :

A

Degenerative changes in vertebral bodies discs joints due to age

18
Q

Cervical myelopathy CF:

A

Radiculomyelopathy with

Compression at spinal cord;
UMN signs below lesion (hyperreflexia , spasticity)

Compression at spinal nerve roots ;
LMN findings (atrophy,hyporeflexia) at the same level.

Urinary symptoms
Sensory deficits
Lhermitte sign

19
Q

Radiculopathy
Neck arm pain with 4th 5th digit sensory deficit

A

C8 radiculopathy (nerve root compression)

Neck movements worsen the impingement causing radiation down the arm.

20
Q

Mechanism of radiculopathy

A

Compression of nerve root ;

Disc herniation
Osteophytes (spondylosis is degeneration of disc and bones in neck)

21
Q

Radiculopathy dx and ttt

A

Clinical

Ttt: Gradual resolution
NSAIDS and avoidance of provocative maneuvers.
Moderate physical activity
Oral steroids for severe pain

Indications for MRI:

MRI only when malignancy or abscess is suspected , progressive symptoms , B/L symptoms.
Xray has limited use

22
Q

Patient with right arm pain , loss of biceps reflex on rt side and loss of elbow flexion. Pain improved with shoulder abduction.

A

C6 radiculopathy

Reflexes : biceps brachioradialis
Sensory : thumb , index finger
Weaknes :
Elbow flexion(biceps)
Forearm supination pronation (brachioradialis)
Wrist extension

23
Q

Radiculopathy pain pattern

A

Shoulder abduction reduces tension on impinged nerve and improves pain when hand is placed on top of head
Shoulder abduction relief test

Lateral flexion and rotation of neck (cradling phone between head and shoulder) narrows neural foramina worsening compression on nerve root.

24
Q

C6 radiculopathy vs median nerve injury

A

Median nerve would not cause neck pain

25
C5 radiculopathy
Reflex. Biceps Sensory. Lateral arm Weakness: Shoulder abduction (deltoid) Elbow flexion (biceps) Vs rotator cuff injury; weakness of shoulder abduction but biceps reflex unaffected
26
Cervical facet dislocation mechanism
Forced flexion of cervical spine (falling onto flexed neck ) Usually single facet dislocated hence UL symptoms
27
Cervical facet dislocation common affected vertebral bodies
C5/6 : C6 radiculopathy Weakness of wrist extension Sensory at forearm and thumb C6/7: C7 radiculopathy Weakness triceps extension Wrist flexion Sensory index and middle finger
28
Fetal alcohol sundrome
Microcephaly Small palpebral fissures Midface hypoplasia Smooth philtrum Thin vermillion border
29
Fetal hydantoin syndrome
In utero phenytoin exposure Midface hypoplasia Cardiac defects Microcephaly Hypoplastic digits / nails Cleft lip palate
30
Digeorge 22q11
Ocular hypertelorism Low set posteriorly rotated ears Interrupted aortic arch Craniofacial anomalies Dev delay
31
Symtoms of IVH
Acute neurologic changes Lethargy Hypotonia Seizures Anemia Bulging fontanelle Rapidly inc head circumference Bradycardia (cushing reflex) Apnea
32
Apnea of prematurity cause
Immature central resp centers in pons and medulla