13. Post-resuscitation care Flashcards

1
Q

what does the post-cardiac arrest syndrome comprise?

A

post arrest brain injury
post arrest myocardial dysfunction
systemic ischaemia/ reperfusion response
persistent precipitating pathology

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2
Q

significant myocardial dysfunction is common after cardiac arrest but typically starts to recover how long after?

A

by 2-3 days (full recovery may take much longer)

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3
Q

approach to the patient following ROSC?

A

ABCDE

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4
Q

aim sats of what following ROSC?

A

94-98%
(some studies suggest an association between hyperoxaemia and poor outcome)

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5
Q

why is achieving normocapnia important to post-arrest neurological function?

A

hypercapnia increases cerebral blood flow/ blood volume and intracerebral pressure

hypocapnia causes vasoconstriction that may decrease blood flow and cause cerebral ischaemia

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6
Q

a tracheal tube that has been inserted too far will tend to go down the ____ main bronchus

A

right
therefore failing to ventilate the left lung

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7
Q

what can be done following ROSC to decompress the stomach, prevent splinting of the diaphragm and enable drainage of gastric contents

A

insert a gastric tube

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8
Q

following ROSC, what does grossly dilated neck veins when the pt is semi-upright indicate about the heart?

A

may indicate right ventricular failure
in rare cases could be pericardial tampondade

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9
Q

T/F: prolonged CPR is a contraindication to fibrinolytic therapy

A

false

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10
Q

GCS score

A

Eyes
1- nil
2- to pain
3- to voice
4- spontaneously

Verbal
1- nil
2- sounds
3- words
4- confused
5- normal

Motor
1- nil
2- extension (decerebrate)
3- abnormal flexion (decorticate)
4- normal flexion
5- localises
6- obey commands

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11
Q

T/F: bicarbonate is recommended in the treatment of acidaemia post arrest

A

false - it may, paradoxically, increase the intracellular acidosis, as it’s converted to CO2 with the release of hydrogen ions within the cell

only indicated post arrest ass with hyperkalaemia or TCA overdose

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12
Q

investigations to order following ROSC?

A

FBC - exclude anaemia
Biochem - renal function, electrolytes, glucose, trops
ECG- cardiac rhythm, evidence ACS, evidence of primary arrhythmogenic causes e.g. Brugada, long QT
CXR- position of tracheal tube/ gastric tube/ central venous catheter, evidence pulmonary oedema/ aspiration/ pneumothorax/ cardiac contour
ABG- adequacy of ventilation and oxygenation, correction of acid/ base imbalance
ECHO- identify contributing causes, assess LV and RV structure and function
CT- exclude IC bleed or stroke as cause, exclude PE or other resp causes

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13
Q

post resuscitation myocardial dysfunction often requires ____ support, at least transiently

what meds are used for this most often?

A

inotropic

noradrenaline with or without dobutamine and fluid is usually most effective

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14
Q

post arrest, if treatment with fluid resuscitation, inotropes and vasoactive drugs is insufficient to support the circulation, consider insertion of what device?

A

an intra-aortic balloon pump (IABP)

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15
Q

immediately after cardiac arrest there is typically a period of ___kalaemia

A

hyperkalaemia

subsequent endogenous catecholamine release and correction of met resp acidosis promotes intracellular transportation of potassium&raquo_space; hypokalaemia

give K to maintain conc 4 - 4.5

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16
Q

what pts should be considered for ICD post arrest?

A

any pt who had a shockable rhythm outside the context of proven acute ST-segment elevation MI

all need cardio review before discharge

17
Q

T/F: immediately after ROSC there is a period of cerebral hyperaemia

A

true

in many post arrest pts cerebral autoregulation is impaired and very dependent on MAP - ie can get hypoperfusion if MAP low or hyperaemia and cerebral hypertension if MAP high

18
Q

what is the most common type of clinical seizure in post arrest pts

A

myoclonus (sudden brief shock like involuntary muscle contraction)

19
Q

T/F: post arrest seizures usually develop in the first 1-2 days and are ass with poor prognosis

A

true

20
Q

how to treat post arrest seizures?

A

levetiracetam and/ or sodium valproate
after the first event start maintenance therapy

21
Q

T/F: prophylactic antiepileptic drugs should be used in post arrest pts

A

false - currently no evidence for this

22
Q

maintain blood glucose in what range following ROSC?

A

</= 10
whilst avoiding hypoglycaemia (<4)

23
Q

continuously monitor core temperature in comatose pts post ROSC

HYPOTHERMIA/ PYREXIA is common in the first 2-3 days following arrest and is associated with a poor outcome

treatment of any pyrexia post arrest?

A

pyrexia

antipyretics, active cooling (blankets, pads, water, air circulating blankets, IV heat exchanger)

actively prevent fever for at least 72hrs post arrest in those who remain comatose (temp >37.7)

24
Q

T/F: comatose pts with mild hypothermia following ROSC should be actively rewarmed

A

false - not recommended (aiming to avoid pyrexia for first 72hrs)

25
Q

T/F: rapid pre-hospital cooling using large volumes of cold IV fluids is recommended in any pyrexia pt following ROSC

A

false - not recommended

26
Q

prognostication of the comatose pt post arrest should be multimodal and involve the following tests
1) clinical examination including…
2) neurophysiological studies including…
3) biochemical marks - the most commonly used is…
4) imaging studies- including…

A

1) GCS, pupil response to light/ corneal reflex, presence of seizures
2) SSEPs, EEG
3) neuron specific enolase
4) CTB and MRI

27
Q

T/F: neurological outcome is considered to be good for the majority of cardiac arrest survivors

A

true

28
Q

T/F: long term cog impairments are present in 1/2 of survivors of cardiac arrest

A

true - memory if most frequently affected, followed by problems in attention and executive functioning (mostly mild impairments)