13/14: Anesthesia in Dogs & Cats Flashcards
What is a common way to prevent peri-anesthetic nausea and vomiting?
Maropitant - 1.0 mg/kg 1 hour before opioid administration
When is injectable maropitant given to cats?
20 hours prior to dexmetetomidine + morphine
What is the result of giving cats injectable maropitant pre-op?
Significant decrease in vomiting, no significant decrease in nausea
When is oral maropitant given to cats pre-op?
2-18 hours prior to dexmedetomidine + morphine
What is the result of giving cats oral maropitant pre-op?
Significant decrease in vomiting but not signs of nausea
When are dogs treated with maropitant pre-op?
45 min prior to morphine
When do dogs return to normal feeding PO if treated with maropitant?
20 hours
What is the consumption difference in dogs pre-tx with cerenia vs those that are not?
Pre-tx = higher mean total food consumption (4.85x more food)
T/F: Owners generally do not worry that their pets will have nausea and vomiting related to surgery
False
What % of owners would probably or definitely choose treatment for nausea? Vomiting?
Nausea = 95.7%
Vomiting = 99%
What % of owners were likely to accept nausea/vomiting treatment for their pets if veterinarian recommended?
95%
Generally, what effects do opioids have on CV, MAC, and respiration?
Mild CV effects, decreased MAC, bradycardia, resp depression
What type of drug is butorphanol?
K agonist/Mu antagonist
Does butorphanol provide sedation/analgesia?
Yes, mild to both
How long does sedation from butorphanol last?
1-2 hours
How long does analgesia from butorphanol last?
~90 min
Does butorphanol have a ceiling effect?
Yes
What is butorphanol used for?
Non or mildly painful procedures
What type of drug is buprenorphine?
Partial mu agonist
Does buprenorphine provide sedation/analgesia?
Yes: little sedation, mild to moderate analgesia
What does it mean when we say that buprenorphine is “sticky” to the mu receptor?
It is difficult to reverse or to follow with a mu agonist
What is the onset of buprenorphine? Duration?
Onset = 30-45 min (slow)
Duration = 4-10 hours in dogs, 6-12 hours in cats
Does buprenorphine have a ceiling effect?
yes
What are the full mu agonists?
Hydromorphone, Morphine, Oxymorphone, Methodone, Fentanyl