13/01 Flashcards
1
Q
What are the indications for parathyroidectomy?
A
Age <50 Symptomatic disease Calcium level >0.25 more than upper normal limit eGFR <60 Renal stones Osteoporosis
2
Q
What should be measured to confirm a diagnosis of acromegaly?
A
Insulin like growth factor 1
3
Q
How can papillary thyroid cancer be diagnosed?
A
Via the presence of Psammomma calcification on histology
4
Q
What is the pathology of MEN1?
A
Autosomal dominant Parathyroid tumour Pancreatic tumour Pancreatic islet cell tumour Pituitary tumour
5
Q
What is the pathology of MEN 2a?
A
Autosomal dominant
Thyroid medullary carcinoma
Pheochromocytoma
Parathyroid tumour
6
Q
What is the pathology of Men 2b?
A
50% autosomal dominant and 50% due to de novo mutations
Thyroid medullary carcinoma
Phaeochromocytoma
Mucocutaneous ganglioneuromas
