1.2 - Musculoskeletal System Flashcards

1
Q

What 3 components make up the musculoskeletal system

A
  • Bones (and joints)
  • Skeletal muscle
  • Connective tissues
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2
Q

Functions of bone

A
  • Support (mechanical support structure)
  • Protection (ie ribs for softer organs inside)
  • Metabolic (calcium etc)
  • Movement (joints)
  • Storage
  • Haematopoiesis
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3
Q

Functions of skeletal muscle

A
  • Locomotion
  • Posture (maintaining good posture by low-level constant contraction)
  • Metabolic
  • Venous return (by squeezing the veins → increase pressure → transport blood back to the heart from the lower extremities)
  • Heat production (thermogenesis via shivering)
  • Continence (sphincters to prevent unwanted release of excretion)
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4
Q

Different types of connective tissues + their functions

A
  • tendons (involved in force transmission muscle–bone)
  • ligaments (support bone-bone)
  • fascia (sheets of connective tissue) for compartmentalisation and protection
  • cartilage
    ☞ articular: decrease friction
    ☞ fibrocartilage: shock absorbtion + increasing bony congriguity
  • synovial membrane secretes synovial fluid for joint and tendon lubrication
  • bursa are synovial fluid-filled sacs to protect tendons, ligaments etc from friction
    note: synovial membrane + bursa are not always considered connective tissue
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5
Q

What is the difference between tendon, ligaments and aponeuroses

A

Tendon: connects muscle + bone
Ligament: connects bone + bone
Aponeuroses: connect muscle + muscle (but sometimes to bone)

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6
Q

What are the 3 main cells found in bones + what are their functions

A
  • osteoblasts are the builders
  • osteoclasts cells that destroy bone, liberating calcium + phosphates. Very similar to macrophages. Release acidic vesicles onto surface of bone to dissolve it
  • osteocytes are osteoblasts that have become trapped within the extracellular matrix. These maintain the bones. Send out cytoplasmic projections, communicate with other osteoblasts + osteocytes and involved in bone remodelling.
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7
Q

Classification of bones

A
  • long ie humerus, tends to be levers
  • short ie in wrist + ankels, act co-operatively in groups to perform functions
  • flat ie sternum, act as shields to protect underlying structures
  • irregular ie vertebrae
  • sesamoid ie patella, form within tendons
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8
Q

What are some surface features of bones

A
  • grooves for nerves to run in
  • notches eg greater sciatic notch, permitting the sciatic nerve to run by
  • foramina are holes within the bone. These can be large or smaller, such as the smaller nutrient foramina that form on the surface, allowing blood vessels to travel through
  • fossa are basin-like depressions
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9
Q

Blood supply to bones

A
  • The nutrient artery enters the diaphysis (shaft) of the bone and supplies blood to the inside of the bone. Most of the bone is dependent on this artery
  • There are also periosteal arteries that supply the periosteum and outer third cortex of the bone
  • In some bones there are the metaphyseal arteries and these enter the site of attachement of the capsuloe
  • In children, these metaphyseal arteries do not cross the growth plate, so the epiphyseal artery supplies the secondary ossification centre in the epiphysis. When the growth plate disappears, an anastomosis is formed between the epiphyseal and metaphyseal arteries
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10
Q

What is avascular necrosis

A
  • When bone dies
  • Occurs when bone is deprived of sufficient blood supply
  • Particular important in fractures, where they could be cutting off blood supply to the bone
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11
Q

Features + main classification of joints (more detail on other cards)

A
  • Joints connect one bone to another
  • There is a balance between the range of movement vs stability (ie probability of dislocation)
  • Ie shoulder joints need good range of movement, whereas skull bones don’t
  • They are classified as fibrous, cartilaginous and synovial
  • Fibrous = most stable with lowest RoM
  • Synovial = least stable with highest RoM
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12
Q

Fibrous joints

A
  • Most stable type of joint, but a low range of movement
  • Essentially two adjacent bones glued together by collagen
  • Found where great strength + stability are needed eg skull, teeth
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13
Q

Cartilaginous joints

A
  • Somewhere in the middle – somewhat stable and a fair range of movement
  • Cartilage acts as a glue holding two adjacent bones together
  • Typically found at the ends of growing bones or along the midline of the adult body
  • primary are found in growing skeleton ie at growth plates
  • secondary are found in pubic bones and in between vertebrae
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14
Q

Synovial joints

A
  • Separate bones that are capped with smooth articular cartilage, with a thin film of synovial fluid separating them
  • Leads to a very low friction environment
  • Feels like egg whites
  • Often highly mobile, but not very stable
  • Found all over the skeleton
  • Joint capsule and periosteum surround the joint
  • Around the synovial fluid is the synovial membrane (this also secretes the fluid)
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15
Q

Types of synovial joint (probably also need to identify from photos

A
  • Plane where two flat surfaces slide against each other, allowing for smooth movement in several directions along a single plane. Eg carpal bones of the wrist.
  • Hinge allow for flexion + extension without sliding or deviation. Movement only occurs along a single plane. Eg elbow joint
  • Pivot comprise a peg within a ring-shaped hole. Allow rotational motion without gliding. Eg atlanto-axial joint that allows the head to rotate whilst maintiaining the stability of the head on the neck
  • Saddle two bones that fit together like a rider in a saddle. Allows motion in two different planes at the same time. Eg carpometacarpal joint at the base of the thumb
  • Condyloid aka ellipsoid are similar to plane joints, but like two elliptical bowls nested together. Unlike B+S joints, they prevent rotation from occurring due to their shape. Eg atlanto-occiptal joint at the base of the skull
  • Ball and socket allow stable movement in several directions without slippage. Most mobile type of synovial joints. Eg hip and shoulder joints
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16
Q

Development of synovial joints (know in general detail)

A
  • Starts with a rod of cartilage
  • interzone condensation where the cells in the middle of the rod will die, leaving a gap where the joint will form
  • joint specification where different chondrocytes will migrate depending on the type of joint being formed
  • secondary structure is formed involving progenitors of the ligaments, synovial membranes and articular progenitors
  • Around the rod of cartilage is connective tissue, which will go on to form the periosteum + joint capsule around the joint
  • A synovial joint is simply an ‘interruption’ in the cartilage model of a bone
17
Q

What is a bursa

A
  • A small sac lined by synovial membrane
  • Contains a thin layer of synovial fluid
  • Provides a cushion between bones, tendons, muscles around a joint
  • This helps to reduce friction between the bones and allows free movemtn
18
Q

The synovial fluid

A
  • Clear/pale yellow, viscous
  • Slightly alkaline
  • Main functions are to reduce friction, act as a shock absorber and to transport nutrients to (and remove waste from) the articular cartilage of the joint
19
Q

Classes of levers

A

class 1
- Eg a pair of scissors
- Effort = the fingers pulling the upper handle of the scissors downwards
- This raises the load that is resting on the lower blade
- effort is applied on the opposite side of the fulcrum to the load

class 2
- Eg a wheelbarrow
- Effort is exerted by pulling up on the handles of the wheelbarrow
- Load is situated in wheelbarrow itself
- the load being lifted lies between the fulcrum and the effort that is applied to lift the load

class 3
- Eg a set of forceps
- Fulcrum is found where the two prongs of the forceps intersect at the hinge
- Effort is applied by lifting the lower prong upwards
- the effort is applied between the fulcrum and the load

20
Q

Muscles concepts

A
  • The insertion is the mobile attachment point and is usually sited distally in the limb
  • Muscle contraction is symettrical, exerting equal force on the origin and the insertion
  • Muscles can only pull, they cannot push
  • Muscles can only act on the joints they (and their tendons) cross
  • The action of a muscle on a joint is dependent on the orientation of its fibres and the relation of those fibres to the joint
  • Muscles work together (almost never in isolation), and the CNS co-ordinates this
  • Muscles are found within fascial compartments
  • The muscles within a compartment generally share a common innervation and action
21
Q

What is the insertion and origin of a muscle

A
  • The origin is the stationary anchor point and is usually sited proximally in the limb
  • The insertion is the mobile attachment point and is usually sited distally in the limb
  • Origin and insertion can be ‘inverted’ if the insertion point is fixed
22
Q

What are the different types of muscle contraction (3)

A
  • Muscles can only pull, but they don’t always shorten
  • Muscles often work in groups, almost never in isolation
  • concentric ▶︎ muscle pulls while shortening (ie biceps curl)
  • eccentric ▶︎ muscle pulls while lengthening (ie knee extensors walking downhill)
  • isometric ▶︎ muscle pulls while staying same length (ie carrying a load)
23
Q

What are the different types of muscle

A
  • parallel subdivided into strap, fusiform, triangular + fan-shaped. This is where the fibres run parallel to the force-generating axis.
  • pennate have one or more aponeuroses running through the muscle body from the tendon. The fascicles of muscle fibres attach to these aponeuroses at an angle (pennation angle) to the direction of movement. Further classified into unipennate, bipennate or multipennate
  • circular aka spincter muscles. Form concentric rings around a spincter or opening. Attach to skin, ligaments + fascia of other muscles (rather than bone)
24
Q

What type of muscle can contract the most powerfully

A

pennate → can generate more force than a parallel muscle of the same length. This is because a pennate muscle has a greater number of muscle fibres.
☞ however, parallel muscles shorten more, so have greater movement

25
Q

Connective tissue concepts

A
  • Connective tissues are all physically connected to one another
  • There are often different names given to the same thing eg superficial fascia = subcutaneous fat, hypodermis
  • Some fascia are named
  • Adhesion of skin to underlying fascia creates skin creases
26
Q

Different types of connective tissues

A

fascia
- A band or sheet of connective tissue
- superficial fascia ☞ subcutaneous fatty layer found in most regions of the body, and surrounds organs, glands, neurovascular bundles etc. Serves as a storage medium for fat and water, and a passageway for vessels, and a padding for organs.
- deep fascia ☞ thickened elaboration of epimysium enveloping the muscle compartments. Consists of collagen bundles + elastin fibres. It is flexible and able to resist unidirectional forces.
tendons
- Consist of dense regular connective tissue fascicles
- Anchored to bone using sharpey’s fibres
- Have relatively poor blood supply, and low water content so don’t heal quickly after injury
ligaments
- Connect bone to bone
- Consist of dense regular bundles of connective tissue (mainly collagen) protected by dense irregular connective tissue sheaths
aponeuroses
- Sheet like structures that are histologically similar to tendons
- Primary function is to join muslces of the body
- There are some that have lost contact with their original muscle but still serve a useful function