11.8.2013(NEJM) Flashcards

0
Q

cfDNA testing is done at

A

9 weeks

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1
Q

Non invasive prenatal testing for trisomies

A

Cell free fetal DNA testing(cfDNA)

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2
Q

Bruton tyrosine kinase inhibitor

A

Ibrutinib

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3
Q

BTK inhibitor is used in treatment of

A

Mantle cell lymphoma

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4
Q

Cord colitis syndrome

A

Colitis after umbilical cord hematopoietic stem cell transplantation

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5
Q

Causative organism in cord colitis syndrome

A

Bradyrhizhobium enterica

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6
Q

Biomarkers for GVHD

A
Systemic GVHD
 interleukin-2 receptor alpha
 Tumor necrosis factor receptor 1
 Hepatocyte growth factor
 Interleukin 8
Skin GVHD
  Elafin
GIT GVHD
  Regenerating islet derived 3alpha
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7
Q

Glucose levels and dementia

A

Elevated glucose levels is a risk factor for dementia in both diabetics and non diabetics

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8
Q

Features of rubella infection

A

Rash
Fever
Palatal petechiae
Arthralgia

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9
Q

Asthma,gender predilection

A

Men are more affected

After teenage yrs,women are commonly affected

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10
Q

Asthma is common in

Adults or children?

A

Adults

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11
Q

Diagnosis of asthma

A

Airflow obstruction that is partially reversed by inhaled short acting beta agonists
Increase in FEV1 by 12%
Increase of predicted FEV1 by 20 points
Increase in peak expiratory flow of more than 20%(60L/min)
Diurnal variation in PEF of more than 10%

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12
Q

Who is more likely to grow out of asthma?

A

Boys

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