11.2 antivirals Flashcards
1
Q
what are the types of influenza virus?
A
influenza A
- multiple host species
- antigenic drift and shift
influenza B
- no animal reservoir
influenza C
- common cold like
2
Q
what ion channel is on influenza A virus’ and what is its significance?
A
Ion channel M2
significance = can be acted upon by antivirals to reduce symptoms. However these types of antivirals only work on influenza A.
3
Q
what is neuraminidase?
A
a protein on the surface of influenza A
it is essential for virus replication. Targeting this with antivirals will prevent its replication in influenza A.
4
Q
name 5 antiviral drugs
A
aciclovir
zanamivir
oseltamivir
valaciclovir
valganciclovir
5
Q
what are the indications of aciclovir and valaciclovir?
A
HSV/ VZV
