111-120 Flashcards

1
Q

indications for oxcarbazepine

A

seizures

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2
Q

indications for phenobarbital

A

seizures, status epilepticus, sedation

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3
Q

indications for phenytoin

A

seizures, status epilepticus

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4
Q

indications for topiramate

A

seizures, migraine headache prophylaxis, weight loss combined w/ phentermine

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5
Q

indications for carbamazepine

A

seizures, bipolar, neuropathic pain

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6
Q

indications for divalproex

A

seizures, bipolar, migraine prophylaxis

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7
Q

indications for lamotrigine

A

seizures, bipolar

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8
Q

indications for lithium

A

bipolar

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9
Q

indications for gabapentin

A

postherpetic neuralgia, seizures

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10
Q

indications for pregabalin

A

postherpetic neuralgia, diabetic neuropathy, neuropathic pain w/ spinal cord injury, fibromyalgia, seizures

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11
Q

off label use of phenobarbital

A

alcohol withdrawal

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12
Q

which drug interacts with valproic acid

A

lamotrigine

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13
Q

which drug must be titrated long and slow

A

lamotrigine

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14
Q

side effects for oxcarbazepine

A

c: n/v, dizzy, drowsy, fatigue, headache, visual disturbances
s: blood dyscrasias, hyponatremia, delayed hypersensitivity reactions, psychiatric effects, suicidal ideation

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15
Q

side effects for phenobarbital

A

c: CNS depression
s: CNS depression, respiratory depression, CV (hypotension, bradycardia)

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16
Q

side effects for phenytoin

A

c: CNS depression
s: blood dyscrasias, CNS effects, CV effects, hepatotoxicity, delayed hypersensitivity reactions, suicidal ideation

17
Q

side effects for topiramate

A

c: abdominal pain, low appetite, dizziness, fatigue, paresthesia
s: CNS effects, cognitive dysfunction, kidney stones, ocular effects, heat intolerance, suicidal ideation

18
Q

side effects for carbamazepine

A

c: n/v, ataxia, dizziness, drowsiness
s: blood dyscrasias, hyponatremia, cardiac effects, hepatotoxicity, delayed hypersensitivity reactions, CNS effects, suicidal ideation

19
Q

side effects for divalproex

A

c: n/v/d, weight gain, somnolence
s: hepatotoxicity, pancreatitis, thrombocytopenia, suicidal ideation

20
Q

side effects for lamotrigine

A

c: dizziness, drowsiness, somnolence, gait issues, vision changes
s: serious skin rashes/ hypersensitivity reactions, blood dyscrasias, suicidal ideation

21
Q

side effects for lithium

A

cardiac, CNS, dermatologic (acne/psoriasis), n/v/d, hypothyroidism, renal effects, sexual dysfunction, tremor, weight gain

22
Q

side effects for gabapentin

A

c: dizziness, drowsiness, fatigue, gait issues
s: CNS and respiratory depression, hypersensitivity reactions, psychiatric effects, suicidal ideation

23
Q

side effects for pregabalin

A

c: dizziness, drowsiness, visual disturbances, dry mouth, peripheral edema, weight gain
s: CNS and respiratory depression, hypersensitivity reactions, suicidal ideation

24
Q

which drug is teratogenic (associated with fetal harm)

A

divalproex

25
Q

which drugs are strong cyp3a4 inducers

A

phenobarbital, phenytoin, carbamazepine

26
Q

which drug is a weak cyp3a4 inducer

A

oxcarbazepine

27
Q

which drugs require therapeutic drug monitoring

A

phenobarbital, phenytoin, carbamazepine, divalproex, lithium