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Simmons NURP 503 Exam 4 > 11: Immune System > Flashcards

11: Immune System Flashcards

1
Q

IgM, IgG, IgA, IgE, or IgD?

Protective. Lines GI, respiratory, and genital tracts.

A

IgA

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2
Q

B cells or T cells?

IgA

A

B cells

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3
Q

_____ tissue continues to grow until school age.

A

Lymph

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4
Q

What is the NP role in managing infection?

A

Primary prevention. Prevent it in the first place. Identify and respond to infection. Comanage chronic infection with a specialist. Otherwise, send to ID specialist.

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5
Q

When do natural killer cells become involved, primary or secondary immune response?

A

Secondary. Memory B cell encounters antigen. Plasma cells form. IgG, IgA, and IgE are made. Natural killer cells respond.

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6
Q

B cells or T cells?

IgG

A

B cells

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7
Q

IgM, IgG, IgA, IgE, or IgD?

Present in internal and external body fluids.

A

IgE

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8
Q

When are stem cells seeded in the long bones?

A

10 weeks

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9
Q

B cells or T cells?

IgM

A

B cells

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10
Q

Due to lack of IgM, neonates are highly susceptible to _____ organisms.

A

Gram-negative organisms

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11
Q

IgM, IgG, IgA, IgE, or IgD?

Initially high from maternal sources, but taper by 6-8 months. Baby’s production begins at this time.

A

IgG

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12
Q

IgM, IgG, IgA, IgE, or IgD?

Body’s first response to an infection.

A

IgM

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13
Q

B cells or T cells?

IgD

A

B cells

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14
Q

When are stem cells seeded in the liver?

A

5 weeks

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15
Q

IgM, IgG, IgA, IgE, or IgD?

Reaches adult levels by age 7-8.

A

IgG

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16
Q

IgM, IgG, IgA, IgE, or IgD?

Mimics IgA.

A

IgE

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17
Q

By adolescence, _____ starts to wane in size.

A

Thymus

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18
Q

Is the primary or secondary immune response more rapid?

A

Secondary

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19
Q

IgM, IgG, IgA, IgE, or IgD?

Along with eosinophils, responds to allergy and parasitic infections.

A

IgE

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20
Q

B cells or T cells?

IgE

21
Q

B cells or T cells?

From bone.

22
Q

By middle age, thymus is at _____% of its initial size.

23
Q

IgM, IgG, IgA, IgE, or IgD?

Present in all internal body fluids.

24
Q

When is the lowest total Ig level?

A

3-4 months old

25
Innate or acquired immunity? | Natural immunity.
Innate
26
_____ cells become memory cells. In future, can mount specific IgG, IgA, or IgE response.
B cells
27
IgM, IgG, IgA, IgE, or IgD? | Can't cross the placenta and is low in newborns?
IgM
28
When are stem cells seeded in the appendix?
11-12 weeks
29
IgM, IgG, IgA, IgE, or IgD? | Production begins around week 2/13 days and reaches adult levels at age 6-7.
IgA
30
IgM, IgG, IgA, IgE, or IgD? | Unclear significance.
IgD
31
IgM, IgG, IgA, IgE, or IgD? | Remains after an infection has resolved.
IgG
32
T/F Younger people are more prone to autoimmune diseases.
False. Older people are b/c their immune system decreases, leading to infections being able to develop more easily.
33
_____ function (not absolute value) declines after middle age.
T cell
34
When are stem cells seeded in the thymus?
8 weeks
35
When are stem cells seeded in the spleen?
8 weeks
36
Innate or acquired immunity? | Phagocytic cells respond.
Innate
37
When does hematopoiesis begin in the fetal liver?
6 weeks
38
When are adult levels of IgM reached?
1 year old
39
IgM, IgG, IgA, IgE, or IgD? | Some is received via breastmilk.
IgA
40
How do T cells differ in neonates?
T cells are present in high numbers and normal newborns can develop antigen-specific T-cell response.
41
T/F Neonates have impaired phagocytosis.
True. It's possible to have severe immunodeficiency without it being recognized.
42
When are stem cells seeded in the lymph nodes?
11-12 weeks
43
T/F Deficiencies in IG subclasses may exist even when total IG levels are normal.
True. Happens specifically with IgG and IgA.
44
When is IgM made?
During the primary immune response. Antigen is carried to the lymph node. Virgin B cells respond. If affinity for antigen is sufficient, B cell develops into antibody-producing plasma cell. At this point, IgM is made. CD40 glycoprotein acts with CD154 on T cells to proliferate B cells and synthesize IgM.
45
T/F Newborns cannot make specific antibodies until 3-4 months old, which is why breastfeeding is so important.
False. They can make specific antibodies at birth.
46
B cells or T cells? | From the thymus.
T cells
47
T/F Ratio of CD4 to CD8 cells differs in neonates compared to adults.
True
48
When are stem cells seeded in the clavicles?
8 weeks
49
Why do newborns require conjugated vaccines?
Newborns cannot mount an immune response to polysaccharide antigens until after 2 years of age. So polysaccharide vaccines are ineffective.

Simmons NURP 503 Exam 4 (17 decks)

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