1.04 Anti Arrythmic Drugs

Question 1

Wave in ECG that represents Atrial Depolarization

Answer 1

P WAVE

Question 2

Wave in ECG that represents ventricular depolaraztion

Answer 2

QRS wave

Question 3

ECG wave that represents Ventricular Repolarization

Answer 3

T WAVE

Question 4

Part of ECG diagram that represents Conduction time from Atrium to Ventricle

Answer 4

PR interval

Question 5

Part of ECG diagram that represents conduction time for ventricular cell action.

Answer 5

QRS

Question 6

Represents duration of ventricular action potential

Answer 6

QT interval

Question 7

STEPS IN SA AND AV NODE DEPOLARIZATION

Answer 7

Phase 0 - Phase 3-Phase 4

Question 8

SA and AV Node is Mediated by what?

Answer 8

CALCIUM

Question 9

Phase 0 is mediated by what?

Answer 9

Ca channel

Question 10

Phase 3 is mediated by what?

Answer 10

K channel

Question 11

Phase 4 is mediated by what?

Answer 11

Funny sodium channel

Question 12

What ion mediates the depolarization of the ventricles,atria and the Purkinje System?

Answer 12

Na

Question 13

Phase 0 in ventricular muscles is mediated by what ion?

Answer 13

Na Channel

Question 14

Phase 2 in ventricular muscles is mediated by what ion?

Answer 14

Calcium

Question 15

Phase 3 and Phase 4 in ventricular muscles is mediated by what ion?

Answer 15

Potassium

Question 16

The 3 conditions that must coexist for Reentry to occur?

Answer 16

1. There must be an obstacle
2. There must be a unidirectional block at some point in the circuit
3. Conduction time must exceed the effective refractory period.

Question 17

Name an example of a disease in which Re-Entry phenomenon occurs

Answer 17

Wolf Parkinson White Syndrome

supraventricular tachycardia

Question 18

Factors that exacerbate of precipitate arrythmia

Answer 18

Ischemia
Hypoxia
Acidosis or alkalosis
Catecholamine Exposure
Autonomic Influence
Drug Toxicities
Presence of scarred tissues
Overstretching of cardiac fibers

Question 19

> 100 beats per min

Answer 19

Sinus tachycardia

Question 20

<60 beats per min

Answer 20

Sinus bradycardia

Question 21

Paroxysmal Tachycardia occuring in the atrium or the AV node

Answer 21

SVT

Question 22

decreased intesity of QRS complex

Answer 22

Atrial Flutter

Question 23

Unreadable P waves

Answer 23

Atrial Fibrillation

Question 24

Aim of Therapy of Antiarrythmic Drugs

Answer 24

1. Reduce ectopic pacemaker activity

2. Modify conduction velocity

Question 25

How do anti arrythmic drugs reduce ectopic pacemaker activity?

Answer 25

By blocking Na or Ca channels

Question 26

How do anti arrythmic drugs modify conduction velocity?

Answer 26

By reduction of readily available unblocked channels or through the prolongation of recovery time of the channels still able to reach the rested and available state, which increases the ERP.

Question 27

AntiArrythmic Agents (4 types)

Answer 27

Sodium Blockers Beta Blockers Potassium Blockers Calcium Blockers

Question 28

Class 1 Of antiarrythmic drugs

Answer 28

Sodium Channel Blockers

Question 29

Class 1A of Antiarrythmic drugs

Answer 29

Disopyramide Quinidine Procainamide