10.2 Raised Intracranial Pressure Flashcards
Normal intracranial pressure in :
Adults, children, term infant
Adults : 5 - 15 mmHg
Children : 5 - 7mmHg
Term infant : 1.5 - 6mmHg
What value is raised ICP?
> 20mmHg
What does the Monro-Kellie doctrine say
Any increase in the volume of one of the cranial constituents must be compensated by decrease in volume of another
Constituents include
- venous volume, arterial volume, brain, CSF
What can cause raised ICP
Too much blood
- raised arterial pressure - malignant hypertension
- raised venous pressure - SVC obstruction
- intracranial haemorrhage (pics on slide of diff hamemorhages )
Too much CSF
- hydrocephalus
When does raised arterial pressure become a problem for ICP
Only in ‘malignant hypertension’ (typically above 180/210)
Types of hydrocephalus
Congenital
Acquired:
- meningitis
- trauma
- tumour
- haemorrhage
What is seen on CT of hydrocephalus
Enlarged ventricles
Causes of congenital hydrocephalus
Congenital obstruction to CSF flow which can be due to :
- neural tube defect
- aqueductal stenosis
Or COMMUNICATING hydrocephalus (not to do with obstruction)
Due to either
- increased CSF production
- decreased CSF absorption
How does congenital hydrocephalus present
- Sunsetting eyes (downward gaze)
- enlarged head
How is congenital hydrocephalus treated initially ?
Tapping the fontanelle
How is short to medium term drainage of congenital hydrocephalus done?
External ventricular drain (EVD)
- Allows short to medium term drainage
- continuous pressure monitoring
(Pic)
3 Disadvantages of EVD
- Direct pathway for bacteria from skin to brain
- Chamber must be kept at same height as ventricles (hard to move around)
- Not a good long term solution
What is a long term solution for congenital hydrocephalus?
Ventricular shunts
What are the 2 types of ventricular shunts ?
- Ventriculo-peritoneal shunt (more common)
- Ventriculo-atrial shunt ( less common)
Pics
Pros and cons of ventricular-peritoneal shunt
- easier to place, can leave a loop which is good for growing children unlike ventriculo-atrial shunt
- prone to infection
- can kink, block, or displace
What is near the top of both types of shunts and what does it do ?
Omayya reservoir
- has one way valve so CSF doesn’t flow back
- measures pressure (set pressure so CSF drains when above certain pressure)
- attach drain (for CSF to flow when above set pressure )
Cerebral oedemas can lead to raised ICP.
What are the 4 types
- vasogenic
- cytotoxic
- osmotic
- interstitial
(Pic)
What are 3 other things that can cause raised ICP?
- tumour
- abscess
- idiopathic
what is cerebral perfusion pressure ?
Equation for cerebral perfusion pressure ?
CPP is the net pressure gradient causing cerebral blood flow to the brain
CPP = MAP - ICP
Normal values for
- MAP
- ICP
- CPP
MAP - 65-110 mmHg
ICP - 5-15mmHg
CPP - >70mmHg
What does changes in CPP trigger
Cerebral autoregulation
What is the risk in decreased CPP
hypoperfusion
Can lead to stroke etc
What can happen to cerebral autoregulation following injury
The capacity for autoregulation may be completely lost
Or
Threshold for autoregulation may be rest.
How does the CVS system try to compensate for raised ICP?
Cushing’s triad