10.2 GI secretion Flashcards
Which cells secrete gastrin?
G cells
What hormone is secreted by S cells?
Secretin
Which cells secrete CCK?
I cells
What is the role of VIP?
Relax smooth muscle,
What is the role of GIP?
- Reduces gastric acid secretion
- Stimulates insulin release
What does motilin do?
Stimulates small bowel movement (MMC during fasting)
Where is somatostatin secreted?
D cells
What stimulates gastrin secretion?
Food
Gastric distension
Vagal stimulation
↑ gastric pH
What inhibits gastrin secretion?
Somatostatin
Secretin → GIP, VIP, Glucagon
Acid pH
What is the role of gastrin?
Stimulates HCl secretion (parietal cells)
Stimulates pepsinogen secretion (chief cells)
What is the role of secretin?
↑ HCO3- from pancreas
↓ gastrin
What is the role of CCK?
↑ gallbladder activity