101-116 Flashcards
Tx for EGPA
steroids (+ cyclophosphamide if severe)
Criteria for EGPA Dx (4/6 required)
asthma, Eos >10%, mono- or poly-neuropathy, migratory pulm opacities, paranasal sinus abnormalities, and extravascular Eos on biopsy
2 ways in which NIV unloads the ventilatory muscles
fewer breaths; less muscle load per breath
main respiratory stimulus post-apnea
hypercapnia
What causes low DLCO in emphysema?
decreased alveolar surface area
2 ways to prevent VAP
subglottic secretion suctioning, oral hygiene (also SAT/SBT, HOB 30-45°, ppx Abx, automatic cuff pressure, ultrathin ETT)
Mepolizumab binds to _____.
alpha-subunit of IL-5
fungal assay for presumptive Dx of PJP
β-d-glucan
definitive Dx of PJP requires _____
staining or PCR of respi specimen
main opportunistic infections in PAP
Nocardia, mycobacteria, and endemic/opportunistic fungi