100 Maternal emergencies after 20 weeks of pregnancy Flashcards
Chronic hypertension in pregnancy is defined as a
Chronic hypertension in pregnancy is defined as a systolic blood
pressure of ≥140 mm Hg or a diastolic blood pressure of ≥90 mm Hg
that existed prior to pregnancy, is diagnosed before the 20th week of
gestation, or persists longer than 12 weeks after delivery.
Severe chronce hypertension in pregnancy defined as
Severe chronic
hypertension is systolic blood pressure >160 mm Hg or diastolic pressure
>110 mm Hg.
omen with chronic hypertension are at increased
risk for
placental abruption, preeclampsia, low birth weight, cesarean
delivery, premature birth, and fetal demise.2,3
Gestational hypertension
hypertension present only after the 20th week of pregnancy or in the immediate postpartum period but without proteinuria.
Safe treatment options for hypertensive women who are pregnant
labetalol, methyldopa, nifedipine, and hydralazine.4 All antihypertensive drugs cross the placenta
First line agents for chronic hypertension and Price pregnancy with those
Starting dose is 100 mg PO twice a day and the usual maintenance dose is 200 to 400 mg twice per day
What drug is usually added when labetalol and methyldopa are not adequately controlling on blood pressure?
Nifedipine.i
Medications and doses of acute management of hypertensive emergency and pregnancy
Hydralazine 5 mg IV or IM, labetalol 20 mg IV, or nifedipine 10 to 30 mg PO
What is the definition of pre-clamp Sia
Presence of de novo hypertension after 20 weeks of gestation combine with protein urea or other maternal organ dysfunction ( Reno liver neurologic).
Severe features of preeclampsia
Systolic blood pressure greater than 160 or diastolic blood pressure greater than 110 on two occasions at least four hours apart. Thrombocytopenia less than 100,000. Impaired liver function tests. Progressive renal insufficiency. Pulmonary Dema. Everybody’s visual disturbances.
Medications and doses of acute management of hypertensive emergency and pregnancy
Hydralazine 5 mg IV or IM, labetalol 20 mg IV, or nifedipine 10 to 30 mg PO
First line agents for chronic hypertension and Price pregnancy with those
Starting dose is 100 mg PO twice a day and the usual maintenance dose is 200 to 400 mg twice per day
What drug is usually added when labetalol and methyldopa are not adequately controlling on blood pressure?
Nifedipine.i
Severe features of preeclampsia
Systolic blood pressure greater than 160 or diastolic blood pressure greater than 110 on two occasions at least four hours apart. Thrombocytopenia less than 100,000. Impaired liver function tests. Progressive renal insufficiency. Pulmonary Dema. Everybody’s visual disturbances.
Laboratory evaluation for HELLP
CBC with differential, creatinine, LFTs, lactate dehydrogenase, urine protein, protein to creatinine ratio, Uric acid level.
Proposed causes of ecclampsia
At hero’s is and thrombosis lead to placental ischemia and infections. Poor placental perfusion is present to lead to the formation of free radicals, actually distress, and inflammatory responses that may influence the mechanistic development of preeclampsia