10 - Forensic Aspects of Drug Abuse 3

Question 1

What is PCP?

Answer 1

• Dissociative anesthetic w/ hallucinogenic properties

- First developed as IV anesthetic for humans, but d/c due to undesirable side effects (convulsions, hallucinations)

Question 2

Drugs related to PCP?

Answer 2

• Ketamine

- Dextromethorphan

Question 3

Methods of ingestion of PCP?

Answer 3

• Smoked (most common)
• Oral
• Injection

Question 4

Desired effects of PCP

Answer 4

• Intense euphoria
• Hallucinations
• Relaxation
• Dissociation from environment

Question 5

Toxicity effects of PCP

Answer 5

• Delirium
• Hallucinations
• Convulsions
• Violent reactions

Question 6

Can tolerance develop w/ PCP?

Answer 6

Yes

Question 7

Can physiological and psychological dependence develop w/ PCP?

Answer 7

• Psychological = yes

- Physiological = no

Question 8

What is GHB?

Answer 8

• Gamma hydroxybutyrate

- CNS depressant, used as a date rape drug

Question 9

Desired effects of GHB?

Answer 9

• Relaxation
• Sense of wellbeing
• Loss of social inhibitions

Question 10

Properties of cannabis

Answer 10

• CNS depressant
• Stimulant
• Hallucinogenic

Question 11

Desired effects of cannabis

Answer 11

• Euphoria
• General sense of wellbeing
• Relaxation
• Loss of inhibitions

Question 12

Adverse effects/ toxicity effects of cannabis

Answer 12

• Fearfulness
• Anxiety
• Mild paranoia
• *Oral ingestion is more of a problem for toxicity

Question 13

Uses of medical marijuana

Answer 13

• Antiemetic
• Management of glaucoma
• Antispasmodic
• Appetite enhancer
• Treatment of chronic pain

Question 14

What is heroine?

Answer 14

• CNS depressant

- Semi-synthetic opioid –> produced by treating morphine w/ acetic anhydride

Question 15

Methods of ingestion of heroine

Answer 15

• Injection
• Smoking
• Snorting

Question 16

Desired effects of heroine

Answer 16

• Euphoria
• Sense of well-being
• Relief of pain
• *Constricted pupils are characteristic of heroine and other opioids

Question 17

Toxicity effects of heroine

Answer 17

• Respiratory depression
• Coma
• Death

Question 18

Can tolerance to heroine develop?

Answer 18

Yes, develops quickly

Question 19

Can psychological and physiological dependence to heroine develop?

Answer 19

• Yes

- Physiological dependence characterized by insomnia, vomiting, diarrhea, hot and cold flashes, weakness, cold-like sx

Question 20

What is important about heroine detection procedures?

Answer 20

• Not detected in body fluids

- Requires special extraction procedure