10. Abdominal Pain in Pediatrics Flashcards

1
Q

Describe: Visceral (splanchnic) pain (4)

A
  • due to noxious stimuli (usually stretch) stimulating receptors of the visceral peritoneum, mesentery, or the muscle or mucosa of hollow organs.
  • The associated afferent autonomic nerves have few nerve endings, innervate targets in a bilaterally symmetric fashion, are unmyelinated, and enter spinal cord at multiple levels.
  • Thus, visceral pain is dull, poorly localized, and associated with the midline.
  • Pain generally sensed in areas corresponding to embryonic origin of affected structure:
    • Foregut (esophagus to duodenum at major duodenal papilla, liver, gallblad- der, pancreas)—epigastric
    • Midgut (distal 2nd part of duodenum to proximal two-third of transverse colon)—periumbilical
    • Hindgut (distal one-third of transverse colon to rectum)—suprapubic/ hypogastric
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2
Q

Describe: Parietal (somatic) pain (3)

A
  • due to noxious stimuli (stretch, inflammation/irritation, tearing) stimulating receptors of the parietal peritoneum, skin, or skeletal muscle.
  • Associated somatic afferent nerves are numerous, myelinated, and transmit to a specific dorsal root ganglion.
  • Thus, somatic pain is relatively more intense and localized, on the same side and dermatomal region as origin of pain.
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3
Q

Describe: Referred pain (2)

A
  • due to convergence/shared projections of somatic and/or visceral pain pathways in the CNS.
  • For example, pneumonia may present as abdo pain due to parietal pleural pain referred to abdo wall.
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4
Q

Name causal conditions of acute abdominal pain in pediatrics: Upper/Epigastric (6)

A
  • Hepatobiliary/pancreatic: acute hepatitis, cholecystitis, cholelithiasis, cholangitis,* acute pancreatitis
  • Esophagus: foreign body ingestion, esophagitis (reflux, chemical, infective, traumatic)
  • Stomach: gastritis, reactive gastropathy, or peptic ulcer (infectious, medications, autoimmune, stress, trauma), foreign body ingestion/bezoar, pyloric stenosis
  • Small intestine: duodenal ulcer, small bowel volvulus*
  • Spleen: infarction, rupture*
  • Functional dyspepsia
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5
Q

Name causal conditions of acute abdominal pain in pediatrics: Lower/Hypogastric (5)

A
  • Intestinal: gastroenteritis, constipation, appendicitis/Meckel diverticulitis causing focal peritonitis,* IBD
  • Mesenteric lymphadenitis
  • Urinary tract: UTI/pyelonephritis, urolithiasis
  • Male genital: incarcerated inguinal hernia,* testicular torsion*
  • Gynecologic: ectopic pregnancy,* threatened abortion, pelvic inflammatory disease, ovarian torsion,* endometriosis, dysmenorrhea, Mittelschmerz, hematocolpos
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6
Q

Name causal conditions of acute abdominal pain in pediatrics: Generalized or Periumbilical (8)

A
  • Intestinal
    • Inflammatory: infectious gastroenteritis, appendicitis,* Meckel diverticulitis,* allergy, IBD, Henoch-Schonlein Purpura (HSP), Hirschsprung, or necrotizing enterocolitis*
    • Obstruction*/dysmotility: constipation, Hirschsprung disease (HD), intussusception, malrotation with volvulus, meconium ileus, distal intestinal obstruction syndrome (DIOS), appendicitis, Meckel diverticulitis, adhesions, duodenal/intes- tinal atresia, bezoar/foreign body, strictures
    • Malabsorption: secondary lactase deficiency, dietary protein-induced enteropathy/ enterocolitis
  • Peritoneal*: abdo trauma, ruptured viscus, primary/secondary bacterial peritonitis, autoinflammatory disease (e.g., Familial Mediterranean fever)
  • Metabolic*: diabetic ketoacidosis, hypoglycemia, adrenal insufficiency
  • Hematologic: sickle cell acute pain crisis, hemolytic uremic syndrome
  • Drugs/toxins*:many (e.g.,consider lead/iron poisoning, salicylates, acetaminophen)
  • Referred: pneumonia, pharyngitis, myocarditis/pericarditis
  • Infantile colic
  • Functional abdo pain, irritable bowel syndrome, abdo migraine
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7
Q

Name causal conditions of CHRONIC abdominal pain in pediatrics: Upper/Epigastric (6)

A
  • Esophagus: esophagitis (reflux, immunologic, infectious, systemic disease associated)
  • Stomach: gastritis, reactive gastropathy, peptic ulcer (infections, medications, eosinophilic, immune-mediated), bezoar or foreign body
  • Duodenum: peptic ulcer, inflammation (celiac disease, eosinophilic gastroenteritis)
  • Hepatobiliary: biliary dyskinesia, chronic hepatitis, cholelithiasis, choledochal cyst
  • Pancreatic: chronic pancreatitis, pancreatic pseudocyst
  • Functional dyspepsia
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8
Q

Name causal conditions of CHRONIC abdominal pain in pediatrics: Lower/Hypogastric (4)

A
  • Intestinal: gastroenteritis, constipation, IBD, malabsorption, polyps
  • Functional abdo pain, irritable bowel syndrome
  • Gynecologic: pelvic inflammatory disease, endometriosis
  • Urinary tract: ureter pelvic junction obstruction, hydronephrosis, nephrolithiasis
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9
Q

Name causal conditions of CHRONIC abdominal pain in pediatrics: Generalized or Periumbilical (7)

A
  • Inflammatory: IBD, infectious gastroenteritis (parasites, bacteria, viruses), celiac disease, allergy (eosinophilic gastroenteritis, food protein intolerance), collagen
  • Intestinal vascular disease
    • Obstruction/dysmotility: functional constipation, secondary constipation (HD, anorectal malformation, spinal cord abnormalities, etc.), strictures, malrotation (intermittent volvulus), intussusception
    • Malabsorption: carbohydrate intolerance (primary lactase deficiency, overfeed- ing or dietary excess of fermentable oligosaccharides, fructose, sorbitol, etc.), cystic fibrosis
  • Metabolic: adrenal insufficiency, diabetes mellitus, thyroid disease
  • Hematologic: hereditary angioedema, porphyria
  • MSK: muscle strain
  • Neoplastic/anatomic: abdo mass (nephroblastoma, neuroblastoma, germ cell tumor, etc.), GI duplication, polyps, hernias (diaphragmatic, internal, umbilical, inguinal), malrotation (Ladd bands)
  • Functional abdo pain, irritable bowel syndrome, abdo migraine
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10
Q

Describe HX: Abdominal Pain in Pediatrics (10)

A
  • ID: Age, PMHx, presenting symptoms
  • History of Present Illness: Tailor to age of presentation, acuity, and whether appears stable or unstable
  • Features of pain: OPQRST
    • Provocation by: movement (peritoneal irritation), meal (pancreatitis, cholecystitis, gastric ulcer, GERD)
    • Palliation by: emesis (small bowel involvement), defecation (colonic condition), meal (duodenal ulcer)
    • Associated symptoms: fever, weight loss
    • GI: anorexia, dysphagia, heartburn, vomiting (coffee ground), early satiety, diarrhoea or constipation, last BM, melena, hematochezia, urgency/tenesmus, flatus/ bloating/distension, jaundice
    • GU: dysuria, hematuria, polyuria, frequency/nocturia, scrotal pain, vaginal discharge/bleeding, and last menstrual period (normal/abnormal)
  • Recent trauma, infections, treatments (and effects)
  • Infectious risks: travel Hx, infectious contacts/animal exposures, uncooked food, untreated water
  • Past Medical History/PSHx
    • If presentation in newborn/infancy—antenatal/perinatal/neonatal Hx, including age (hours/days) of first meconium
    • Chronic medical conditions (e.g., sickle cell disease, diabetes mellitus, cystic fibrosis)
    • Previous abdo surgeries (risk for adhesions, anastomotic complications)
  • Medications/Allergies/Immunizations
    • Including OTC medications, alternative medicine
  • Nutrition
    • Acute pain: time of last meal, relation to pain
    • Chronic pain: variety, quantity, maladaptive eating habits, relation to pain (food diary)
  • FHx /SHx
    • FHx of IBD, celiac disease, functional bowel disorders, etc.
    • Adolescents—HEEADDSSS Hx (Home, Education, Employment, Activities, Drugs, Diet, Sexuality, Safety, Suicidal ideation/mood)
    • Impacts on daily function (school absenteeism, activities, etc.) and family unit
  • Review of Systems: Extraintestinal symptoms of organic disease
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11
Q

Name causal conditions of abdominal pain in paediatrics according to the age of onset (Figure)

A
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12
Q

Name redflags for an organic pathology (4)

A
  • Pain features: progressive, localized (nonumbilical), wakes from sleep, radiates to shoulder, back, or groin
  • GI sx: dysphagia/odynophagia, anorexia, emesis (bilious, bloody, persis- tent), jaundice, absence of flatus/bowel movements, diarrhea (especially chronic and nocturnal), hematochezia/melena
  • Extraintestinal sx: unexplained fevers, weight loss/failure to thrive, decelerated linear growth velocity, oral ulcers, perirectal disease, arthritis, cough/dyspnea, dysuria/hematuria, vaginal discharge/bleeding, scrotal/ pelvic pain
  • FHx: IBD, celiac disease, peptic ulcer disease
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13
Q

Describe physical exam: Abdominal pain (9)

A
  • General appearance: comfort, positioning, level of consciousness, ill-appearance, malnutrition
  • Vitals/anthropometrics: abnormal growth parameters (failure to thrive), fever, tachypnea/desaturation, hypotension, or unexplained tachycardia
  • Skin: bruising, petechiae/purpura, jaundice, erythema nodosum, dermatitis her- petiformis, etc.
  • HEENT/respiratory: conjunctivitis/episcleritis, oral lesions, cheilitis/glossitis, pharyngeal erythema/exudate, lymphadenopathy, thyromegaly, findings consistent with respiratory infection
  • Cardiovascular: delayed capillary refill, diminished peripheral pulses, muffled/ additional heart sounds
  • Abdo exam: surgical scars, distention, visible bowel loops, altered bowel sounds, focal tenderness, peritoneal irritation (percussive or rebound tenderness, involun- tary guarding), masses, hepatosplenomegaly, ascites
  • DRE: local tenderness, mass, hard stool, blood
  • Perianal/GU: perianal skin tag/abscess, hemorrhoids, anal fissure, imperforate anus, scrotal swelling, incarcerated hernia
  • Pelvic exam: in sexually active females with lower abdo pain
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14
Q

Describe ROUTINE investigations: Abdominal pain (1)

A

No additional evaluation required for children with abdo pain who are otherwise healthy, with normal physical exam and absence of “red flags” for organic disease

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15
Q

Name LAB tests: Abdominal pain (11)

A
  • CBC/differential: high WBC/Plt (infectious/inflammatory), anemia (MAHA, hemoglobinopathy)
  • Serum electrolytes, glucose, creatinine, BUN (metabolic acidosis, DKA, renal pathology, or hypovolemia)
  • Total/direct bilirubin, transaminases, GGT, ALP, amylase, lipase (hepatic, biliary, pancreatic pathology)
  • Antitissue transglutaminase and IgA level (celiac disease screen)
  • Serum/urine b-hCG (if postmenarcheal female)
  • Stool for O&P × 3, C&S, C. difficile PCR, viral culture/electron microscopy
  • Consider stool for fecal fat, occult blood, WBC, reducing substances
  • Urine R+ M , C+ S if indicated
  • Throat swab for culture (streptococcal pharyngitis)
  • Urea breath test or stool H. pylori antigen assay (H. pylori screen)
  • Consider vaginal swabs or urine testing for chlamydia, gonorrhea, trichomonas (if microscopy available)
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16
Q

Name imaging tests: Abdominal pain (6)

A
  • CXR: pulmonary disease, cardiomegaly (myocarditis), foreign body
  • AXR (three views include upright view with visible diaphragms): free air under diaphragm (pneumoperitoneum with ruptured viscus), bowel obstruction/volvulus, nephrolithiasis, constipation, foreign body
  • CT abdo (appendicitis, pancreatitis, intra-abdo abscess, mesenteric ischemia, Abdo mass)
  • U/S abdo (cholelithiasis, cholecystitis, intussusception, appendicitis, hydronephrosis, obstruction)
  • U/S bowel wall or MR enterography (if suspect IBD with small bowel involvement—unable to be determined on upper endoscopy or colonoscopy)
  • U/S pelvis/scrotum (testicular torsion, gynecologic pathology)
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17
Q

Name mainly clinical dx (6)

A
  • Henoch-Schönlein Purpura
  • Appendicitis
  • Infantile colic
  • Incarcerated hernia,
  • Gastroenteritis
  • GERD
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18
Q

Describe HX and Physical exam: Hirschsprung Disease (6)

A
  • HX:
    • Delayed meconium
    • Failure to Thrive
    • Bilious vomiting
    • Chronic constipation since birth
  • Physical exam:
    • Abdo distension
    • Digital Rectal Exam: tight anal sphincter, empty ampulla, blast sign (expulsion of gas and stool after DRE)
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19
Q

Describe investigations: Hirschsprung Disease (2)

A
  • Barium enema:
    • narrow/normal rectum
    • dilated colon proximal to aganglionic segment
    • with transition zone
  • Definitive Dx by rectal biopsy: absence of ganglion cells
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20
Q

Describe HX (4) and physical exam (2): Pyloric stenosis

A
  • HX:
    • Symptom onset 3–8 wk old
    • Failure to Thrive, “hungry vomiter”
    • M>F
    • Projectile nonbilious vomiting, immediately postprandial
  • Physical exam:
    • ± Visible peristalsis
    • Possible palpable epigastric mass (“olive sign”)
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21
Q

Describe investigations: Pyloric stenosis (2)

A
  • U/S: hypertrophied pylorus (increased muscle thickness and length)
  • Lytes/blood gas: hypochloremic, hypokalemic metabolic alkalosis
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22
Q

Describe HX (1) and physical exam (2): Duodenal atresia

A
  • HX: Bilious vomiting within hours of birth (later if stenosis)
  • Physical exam:
    • Epigastric distension
    • 1⁄4 have trisomy 21
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23
Q

Describe investigations: Duodenal atresia (2)

A
  • AXR: “double bubble” sign, absent distal abdo gas
  • Upper GI series: duodenal obstruction
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24
Q

Describe HX (3) and physical exam (1): Infantile colic

A
  • HX:
    • Unexplained paroxysms of irritability, fussiness, or crying starting/ stopping without obvious cause, in < 4 mo old
    • episodes of ≥ 3 h/d, ≥ 3 d/wk, for ≥ 1 wk
    • No failure to thrive
  • Physical exam: Healthy appearing infant
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25
Describe investigations: Infantile colic (1)
Clinical Dx (Rome III criteria)
26
Describe HX (9) and physical exam (2): Gastroesophageal reflux/GERD
* HX: * Regurgitation/emesis * feeding aversion * “colicky baby,” * irritable * Apnea * stridor * aspiration * wheeze * Sandifer syndrome: back arching, chin lifting, neck contortions due to discomfort * Physical exam: * ± FTT (in GERD) * ± Hoarseness/stridor/wheeze
27
Describe investigations: Gastroesophageal reflux/GERD (4)
* Empiric trial of acid suppressant * Endoscopy: esophagitis * 24- ph probe/impedanc study: acidic/nonacidic reflux, strength of association with suspected signs/ symptoms * ± Upper GI series: R/O obstruction/stenosis, malrotation
28
Describe HX (4) and physical exam (4): Incarcerated inguinal hernia
* HX: Classic Hx * swelling in inguinal area during crying/straining * Irritable and crying * Vomiting, abdo distension * Groin pain * Physical exam: * Firm, tender, often edematous inguinal mass * ± Surrounding erythema * ± Abdo distension/tenderness * ± Scrotum appear blue due to testicular venous congestion
29
Describe investigations: Incarcerated inguinal hernia (3)
* Clinical * AXR (may see lower GI obstruction or air bubble in groin) * U/S
30
Describe HX (6) and physical exam (3): Intussusception
* HX: * 3 mo to 3 y.o. (up to 6 y.o.) * Paroxysmal, severe, crampy abdo pain, inconsolable crying, drawing up legs * Episodes progress in frequency * ± Vomiting * Currant jelly stool (blood/ mucous) * Initially comfortable/normal behavior between episodes; progressive lethargy * Physical exam: * Abdo may be benign vs. variable abdo distension and tenderness * ± Palpable sausage-shaped RUQ or epigastric mass * ± Bloody mucus on DRE
31
Describe investigations: Intussusception (2)
* Air contrast enema: obstruction (filling defect), air fluid levels, absence of gas in RLQ * U/S: target sign (bowel within bowel), tubular mass
32
Describe HX (3) and physical exam (2): Malrotation with mid-gut volvulus
* HX: * Sudden onset bilious emesis, abdo distension, melena * Septic shock (necrotic bowel and 3rd spacing) * Children may have episodic abdo pain with vomiting for weeks to years before detection * Physical exam: * Abdo distension/tenderness * ± Peritonitis/shock
33
Describe investigations: Malrotation with mid- gut volvulus (2)
* AXR: upper GI obstruction (dilated proximal loops with fairly gasless abdo), pneumoperitoneum * Upper GI series: failure of duodenum to cross midline (malrotation), duo- denal obstruction (volvulus)
34
Describe HX (8) and physical exam (4): UTI
* HX: * Dysuria * urgency * frequency * Irritability * fever * poor feeding * Vomiting or diarrhea * Flank or abdo pain * Physical exam: * Tender abdo (suprapubic) * ± Costovertebral angle tendernes * Murphy punch sign (in pyelonephritis) * ± Fever
35
Describe investigations: UTI (3)
* Urine R&M (WBC, nitrites, leukocyte esterase) * C&S * Controversy in workup after 1st UTI: renal U/S ± Voiding Cystourethrogram
36
Describe HX (4) and physical exam (3): Constipation
* HX: * BMs: 2 or less per week, large diameter, difficult/incomplete evacuation * Colicky abdo pain, painful defecation * ± fecal incontinence * ± Retentive posturing * Physical exam: * Abdo palpation of hard fecal mass * Dilated rectum filled with stool * ± Anal fissure
37
Describe investigations: Constipation (2)
* Clinical (Rome criteria for functional constipation) * AXR: fecal impaction (excessive stool in colon)
38
Describe HX (4) and physical exam (2): Gastroenteritis
* HX: * Fever, cramping abdo pain * Diarrhea, ± minimal bright red blood per rectum (BRBPR) * Vomiting, anorexia * H/A, myalgia * Physical exam: * Soft, tender abdo * Fever possible
39
Describe HX and physical exam:
* HX: * Physical exam:
40
Describe investigations:
41
Describe HX and physical exam:
* HX: * Physical exam:
42
Describe investigations:
43
Describe investigations:
44
Describe HX and physical exam:
* HX: * Physical exam:
45
Describe HX (4) and physical exam (2): Gastroenteritis
* HX: * Fever, cramping abdo pain * Diarrhea, ± minimal bright red blood per rectum (BRBPR) * Vomiting, anorexia * H/A, myalgia * Physical exam: * Soft, tender abdo * Fever possible
46
Describe HX (2) and physical exam (8): Pneumonia
* HX: * Respiratory tract symptoms N/V * Chest and/or upper abdo pain * Physical exam: * Tachypnea * hypoxia * increased work of breathing * fever * Percussion dullness * increased tactile fremitus * decreased air entry * bronchial breath sounds
47
Describe investigations: Pneumonia (2)
* CXR: focal consolidation, pleural effusion (atypical pneumonia w/ patchy diffuse opacifications) * Possible ↑ WBC
48
Describe HX (5) and physical exam (3): Hemolytic Uremic Syndrome
* HX: * Preceding gastroenteritis * fever, bloody diarrhea (5–10 d) * Abrupt onset of irritability, lethargy * edema * pallor (usually without purpura) * Physical exam: * Toxic, ± uremic encephalopathy * Tender abdo * Hypertension
49
Describe investigations: Hemolytic Uremic Syndrome (4)
* CBCD, blood smear, haptoglobin & bilirubin: MAHA, thrombocytopenia * Cr:↑(ARF) * U/A: proteinuria, hematuria * Stool C&S: infection
50
Describe HX (5) and physical exam (3): Henoch-Schönlein Purpura
* HX: * Colicky abdo pain associated with vomiting (within 8 d of purpuric rash) * Melena/hematochezia * Arthralgias * Hematuria * Rare GI complications: intussusception, pancreatitis, protein- losing enteropathy * Physical exam: * Palpable purpura on lower extremities/gravity dependent areas) * Oligoarthritis * ± Hypertension
51
Describe investigations: Henoch-Schönlein Purpura (5)
* No lab findings diagnostic * Common: increased ESR, CRP, WBC, platelets; anemia * IgA: elevated in 50%–70% * INR/PTT: no coagulopathy * ± Hematuria, proteinuria, ↑ Cr Biopsy skin/kidney (rarely needed); IgA deposition, leukocytoclastic vasculitis
52
Describe HX (3) and physical exam (2): Urolithiasis
* HX: * Colicky abdo/flank pain, radiating to testes or labia * N/V, chills, ileus * Gross hematuria, dysuria, urgency * Physical exam: * Fever * Abdo ± costovertebral angle tendernes
53
Describe investigations: Urolithiasis (3)
* Radiopaque stones on AXR * Non-contras CT gold standard * U/S: obstruction of GU system, Hydronephrosis
54
Describe investigations:
55
Describe HX (4) and physical exam (3): Diabetic Ketoacidosis
* HX: * N/V, anorexia * Dehydration, weight loss * Fatigue * Polyuria, polydipsia, polyphagia * Physical exam: * Dehydration * Diffuse abdo tenderness * Kussmaul breathing
56
Describe investigations: Diabetic Ketoacidosis (3)
* ↑ Blood glucose (\> 11.1 mM) * ABG: WAG metabolic acidosis (Hco3 \<15,pH\<7.3) * Positive urine/serum ketones ± ↑ WBC, Cr, and BUN (hemoconcentration)
57
Describe HX (2) and physical exam (3): Appendicitis
* HX: * Periumbilical pain, migrating to RLQ (worse with cough, walking, jumping) * Anorexia, nausea, vomiting * Physical exam: * Fever * RLQ tenderness (percussion andpalpation)—often focal at McBurney point * ± Peritonism: rebound tenderness, involuntary guarding, Rovsing sign, Obturator sign, Iliopsoas sign
58
Describe investigations: Appendicitis (3)
* U/S: thick-walled/dilated appendix ± appendicolith * CT: enlarged appendix, appendicolith, associated mesenteric fat stranding * ± ↑ WBC, ↑ neutrophils
59
Describe investigations: Appendicitis (3)
* U/S: thick-walled/dilated appendix ± appendicolith * CT: enlarged appendix, appendicolith, associated mesenteric fat stranding * ± ↑ WBC, ↑ neutrophils
60
Describe HX (3) and physical exam (2): Pancreatitis
* HX: * Severe persistent epigastric/LUQ pain radiating to back, alleviated by bending forward * Anorexia, vomiting * Restlessness, agitation * Physical exam: * Fever, tachycardia * Tender ± distended abdo Periumbilical or flank bruising (hemorrhage)—very rare in pediatrics
61
Describe investigations: Pancreatitis (3)
* ↑ lipase , ↑ WBC * U/S: hypoechoic enlarged pancreas ± gallstones * CT: edema, necrosis, hemorrhage, peripancreatic fat stranding, pseudocyst
62
Describe HX (3) and physical exam (4): Cholecystitis
* HX: * Epigastric/RUQ pain steady, severe ± radiation to shoulder/back, worse with motion * Preceded by/associated with fatty meal * Anorexia, N/V * Physical exam: * Fever, tachycardia * Tender abdo * ± guarding * ± Murphy sign
63
Describe investigations: Cholecystitis (4)
* U/S: thick wall, gallstones, dilated gallbladder * ↑ WBC * Bili, ALP, GGT usually normal * hIDA: nonvisualized gallbladder
64
Describe HX (7) and physical exam (2): IBD
* HX: * FTT/weight loss, fatigue * Growth failure, pubertal delay * Red eyes, mouth ulcers * Abdo pain * Perianal disease * Diarrhea ± blood, mucus/pus, urgency, tenesmus * Arthralgia, rashes * Physical exam: * Tender abdo ± RLQ mass * Extraintestinal: fever, episcleritis, oral ulcers, pallor, digital clubbing, erythema nodosum, pyoderma gangrenosum, arthritis/sacroiliitis, perianal disease
65
Describe investigations: IBD (5)
* Anemia (iron deficiency and chronic inflammation) * ↑ WBC and Plts, ↑ ESR/CRP * Low albumin, vitamin D * Stool positive for blood, WBC * Upper endoscopy/colonoscopy, small bowel imaging
66
Describe HX (3) and physical exam (2): Testicular torsion
* HX: * Severe sudden onset testicular or scrotal pain, ± inguinal/lower * Abdo pain * Nausea, vomiting ± fever * Physical exam: * Tender, swollen testicle, elevated ± horizontal lie * Absent ipsilateral cremasteric reflex
67
Describe investigations: Testicular torsion
Scrotal doppler U/S: compromised testicular perfusion
68
Describe HX (3) and physical exam (2): Ectopic pregnancy
* HX: * Sexually active * Missed period * Vaginal bleeding, pelvic pain * Physical exam: * Painful internal pelvic exam * ± Peritonitis
69
Describe investigations: Ectopic pregnancy (2)
* serum b-HCG (slow rise) * Pelvic U/S: absent intrauterine fetus ± visible ectopic pregnancy
70
Describe HX (5) and physical exam (3): Endometriosis
* HX: * Dysmenorrhea * ± Acyclic pelvic pain * Abnormal vaginal bleeding * Urgency, dysuria * Dyschezia, constipation * Physical exam: * General pelvic tenderness * ± Tender uterosacral ligaments, posterior uterus * ± Fixed uterine retroversion
71
Describe investigations: Endometriosis (3)
* Pregnancy test negative * Pelvic U/S: excludes other pathology, may see endometrioma * Laparoscopy
72
Describe HX (2) and physical exam (2): Ovarian torsion
* HX: * Sudden unilateral abdo/pelvic pain * ± N/V * Physical exam: * Painful unilateral adnexa * ± Peritonitis
73
Describe investigations: Ovarian torsion (2)
* Pregnancy test negative * Pelvic U/S: ovarian torsion
74
Describe: Rome III Criteria for Functional Chronic Abdo pain disorders (7)
* All functional disorders→ no evidence of inflammatory, anatomic, metabolic, or neoplastic process to otherwise explain symptoms * Functional dyspepsia: persistent/recurrentupper abdopain/discomfort, ≥1×/wk for ≥ 2 mo * Irritable bowel syndrome: abdo pain/discomfort with ≥ 2 of 3 (pain improved by defecation, associated with change in frequency of stool or form of stool) for ≥ 25% of the time, ≥ 1× /wk for ≥ 2 mo * Childhood functional abdopain: episodic/continuous abdo pain, ≥1×/wk for ≥ 2 mo * Childhood functional Abdo pain syndrome: functional Abdo pain ≥ 25% of the time, with some loss of daily activity, headache, limb pain, or difficulty sleeping * Abdo migraine: intense periumbilical pain for ≥1h, interferes with normal activities, associated with ≥ 2 of 6 (headache, photophobia, nausea, vomiting, pallor, anorexia), intervening usual health * “Recurrent abdo pain” (RomeII): ≥ 3 episodes of pain severe enough to affect daily activities over ≥ 3 mo
75
Describe: Pediatric Appendicitis Score (PAS) (8)
* 1 point for each of: * (1)Anorexia * (2) nausea or vomiting * (3) migration of pain * (4)fever \> 38°C * (5) WBC \> 10× 106/L * (6) neutrophils + band forms \> 7.5 × 106 cells/L * 2 points for each of: * (7) RLQ tenderness * (8) pain with cough or percussion * PAS ≤2: low risk; PAS 3 to 6: intermediate risk → consider surgical consultation, serial exams; PAS ≥ 7: high risk → surgical consultation warranted
76
Describe: Hemolytic uremic syndrome (HUS) (3)
1. Acute kidney injury 2. Thrombocytopenia 3. Microangiopathic hemolytic anemia
77
Name: Diabetic ketoacidosis (DKA) Precipitants (4)
* Insulin deficiency (new Dx or missed insulin dose) * Infection * Ischemia * Intoxication
78
Describe management: Constipation (4)
* Diet modification * bowel routine * increased fluids * behavior modification
79
Describe management: Gastroenteritis (1)
Oral/IV rehydration; treat etiology
80
Describe management: UTI (1)
Antibiotics
81
Describe management: Functional/infantile colic (3)
* Patient/parent education, reassurance * Address psychosocial issues * Consider: allergy, probiotics
82
Describe management: Pancreatitis (6)
* Aggressive fluid resuscitation * Monitor/correct electrolyte/metabolic disturbances * Pancreatic rest (NPO vs. low-fat semi-elemental feeds) if pain limiting intake * Pain management * Broad-spectrum antibiotics if necrosis * Treat etiology
83
Describe management: Henoch-Schönlein Purpura (2)
* Supportive: rest, hydration, nutritional support, analgesia PRN * Systemic corticosteroids for severe GI involvement (controversial)
84
Describe management: Hemolytic Uremic Syndrome (3)
* Monitor/correct fluids and lytes * Red cell and Plt transfusions PRN * Strict control of hypertension and nutrition; possible dialysis
85
Describe management: Acute intestinal obstruction (6)
* Stabilize ABCs * IV fluid resuscitation * Broad-spectrum antibiotics if suspect necrosis/ perforation * NPO/NG tube decompression * Treat etiology * Surgical: * If necrosis/perforation * If no improvement within ~24 h * If “ de novo” or closed-loop obstruction
86
Describe management: Appendicitis (2)
* IV antibiotics if perforated * Appendectomy
87
Describe management: Intussusception (2)
* IV resuscitation, NG decompression Reduction with air contrast enema * Surgical: If symptoms \>24 h or signs of peritonitis
88
Describe management: Incarcerated hernia (2)
* Nonoperative reduction with sedation/analgesia if nonstrangulating * Surgical: If unable to reduce or signs of peritonitis
89
Describe management: IBD (2)
* Immunosuppressive therapy (induction agent) once exclude active infection * Surgical: Bowel resection/stricturoplasty if obstruction refractory to medical management
90
Describe management: Pyloric stenosis (2)
* IV resuscitation and correction of electrolyte derangements if present * Pyloromyotomy
91
Describe management: Malrotation with midgut volvulus (2)
* Fluid resuscitation if hemodynamically unstable * Laparotomy with Ladd procedure
92
Describe management: Duodenal atresia/stenosis (1)
Surgical: Duodenoduodenostomy or duodenojejunostomy
93
Describe management: Testicular torsion (2)
* Attempt at manual detorsion with sedation/ analgesia * Surgical: Detorsion with orchiopexy or testicular removal (if necrotic)