1 - Water and pH Flashcards

1
Q

Causes of high anion gap metabolic acidosis

A

MUDPILES

Methanol
Uremia
Diabetic Ketoacidosis
Paraldehyde and Propylene Glycol
Isoniazid
Lactic acidosis (Sepsis, Shock)
Ethylene Glycol
Salicylates
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2
Q

Negative logarithm of hydrogen ion concentration

A

pH

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3
Q

Any substance that resists a change in pH when protons are produced or consumed

A

Buffer

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4
Q

Chemical compound that has a total net charge of zero

A

Zwitterion

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5
Q

pH at which the zwitterion is the predominant form of a chemical compound

A

Isoelectric pH

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6
Q

used to calculate the concentration of a weak acid (HA) and its conjugate base (A-)

A

Henderson-Hasselbalch equation

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7
Q

If actual pH < pKa substance is

A

Protonated

Base is charged
Acid is uncharged

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8
Q

If actual pH > pKa substance is

A

Deprotonated

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9
Q

Electrons that can form hydrogen bonds

A

SON

Sulfur
Oxygen
Nitrogen

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10
Q

Water molecules have a slight tendency to dissociate and form:

A

Hydronium (H30) and Hydroxide ions (OH)

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11
Q

Most important EXTRAcellular buffer

A

Bicarbonate

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12
Q

Most important INTRAcellular buffer

A

Proteins

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13
Q

This means that water can act both as an acid and a base in a solution

A

Amphoteric

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14
Q

Bond between a water molecule and another polar compound

A

Hydrogen Bond

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15
Q

Accepts H+ ions

A

Base

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16
Q

Donates protons

A

Acid

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17
Q

pKa below 7

A

Acid

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18
Q

pKa above 7

A

Base

19
Q

used to calculate the concentration of a weak acid (HA) and its conjugate base (A-)

A

Henderson-Hasselbalch equation

20
Q

If actual pH < pKa substance is

A

Protonated

Base is charged
Acid is uncharged

21
Q

If actual pH > pKa substance is

A

Deprotonated

22
Q

Electrons that can form hydrogen bonds

A

SON

Sulfur
Oxygen
Nitrogen

23
Q

Water molecules have a slight tendency to dissociate and form:

A

Hydronium (H30) and Hydroxide ions (OH)

24
Q

Most important EXTRAcellular buffer

A

Bicarbonate

25
Q

Most important INTRAcellular buffer

A

Proteins

26
Q

This means that water can act both as an acid and a base in a solution

A

Amphoteric

27
Q

Bond between a water molecule and another polar compound

A

Hydrogen Bond

28
Q

Accepts H+ ions

A

Base

29
Q

Donates protons

A

Acid

30
Q

pKa below 7

A

Acid

31
Q

pKa above 7

A

Base

32
Q

used to calculate the concentration of a weak acid (HA) and its conjugate base (A-)

A

Henderson-Hasselbalch equation

33
Q

If actual pH < pKa substance is

A

Protonated

Base is charged
Acid is uncharged

34
Q

If actual pH > pKa substance is

A

Deprotonated

35
Q

Electrons that can form hydrogen bonds

A

SON

Sulfur
Oxygen
Nitrogen

36
Q

Water molecules have a slight tendency to dissociate and form:

A

Hydronium (H30) and Hydroxide ions (OH)

37
Q

Most important EXTRAcellular buffer

A

Bicarbonate

38
Q

Most important INTRAcellular buffer

A

Proteins

39
Q

This means that water can act both as an acid and a base in a solution

A

Amphoteric

40
Q

Bond between a water molecule and another polar compound

A

Hydrogen Bond

41
Q

Accepts H+ ions

A

Base

42
Q

Donates protons

A

Acid

43
Q

pKa below 7

A

Acid

44
Q

pKa above 7

A

Base