1 ) principles of making rationale drug choices

Question 1

what is the p drug ?

Answer 1

personal or preferred drug , drug that has been selected for regular use and serves the condition

usually dogs offers choice

Question 2

what are the four criteria in choosing a p drug ? and their related percentage to the overall score given ?

Answer 2

efficacy -50 percent score
safety - 30 percent score
suitability = 10 percent
cost = 10 percent

given a score of 1-10 and calculate the given score times it by the percentage

Question 3

what is efficacy ?

Answer 3

the extent which the drug does more good than harm

Question 4

what encompasses safety ?

Answer 4

dose dependant and dose independent adverse reactions

Question 5

what encompasses suitability of a drug ?

Answer 5

age
physiological conditions – pregnancy
concomitant disease - liver or renal
co medication

drugs dosage form inconvenience and dosing schedule

Question 6

hat are the several steps that needs to be passed when coming to a diagnosis of a condition

Answer 6

1) complaints of the patient
2) specifying the therapeutic objective - if the drug is needed ? or what the patients wants goals are
3) verify the suitability of the chosen p drug - not everyone can be given the first choice drugs

4) prescribing the drug
- how the drug should be taken
how many times per day
for how long should the drug be taken
how should the drug be kept

5) giving information , instructions and warnings to the patient
- maximal dose allowed
when not to take the drug

6) monitoring and stopping the treatment
- if the treatment is effective or not
if treatment not effected diagnosis should be reconsidered swell as the drug / or patient not give the right treatment and has not been compliant

Question 7

45 year old man has been diagnosed by arterial hypertension , also have brachial asthma - select the p drug ?

Answer 7

carvedilol - not the first line

Question 8

3 year old boy comes with severe asthma attack for the first time. what is the drug given ?

Answer 8

albuterol in inhalation form

Question 9

pregnant women in her 3rd trim comes with tooth ache - p drug ?

Answer 9

aspirin

Question 10

7 year old comes with cough and fever - diagnosis community acquired pneumonia - p drug

Answer 10

moxifloxacin

Question 11

58 yr old smoker - exacerbations of copd - currently taking simvastatin for high cholesterol - what is the p p drug for exacerbation of copd ?

Answer 11

clarithromycin

Question 12

when conducting trails what is very important ?

Answer 12

gaining consent

in the consent the I’m , risks and conditions which it will take under measured

the right of the patient to refuse further participation at any stage of the trial with no consequence

contact information of a member who can give additional information they have the right to know all the information of the trial

and the patients can understand

to readily report ADR