1. Pancreatic Hormones and Anti-Diabetic Drugs Flashcards
3 hormones secreted by the pancreas?
Insulin
Glucagon
Somatostatin
Peptide hormones are secreted from cells in?
islets of Langerhans
Lack of insulin (in DM) can cause
Hyperglycemia
If DM left untreated it can cause
retinopathy
nephropathy
neuropathy
CV complications
Hypoglycemic hormone?
insulin
Hyperglycemic hormone
glucagon
Secrete digestive juices in the duodenum
Acini
Insulin and glucagon are synthesize as
large preprohormones
Insulin contains how many AA
51 AA (21 and 30) connected by disulfide bridges
Glucagon is a straight-chain polypeptide of how many AA
29 AA residues
Translation happens in…
Ribosomes, specifically cytoplasm
Replication happens in…
Nucleus
Transcription happens in…
Nucleus to cytoplasm
Insulin was first isolated from the pancreas in 1922 by
Banting and Best
Role of insulin in storing excess energy