1. Neurones Flashcards
What is the resting state of a membrane potential ?
Outside of membrane is positively charged compared to the inside of the membrane.
Because more positive ions out side the cell than inside.
Membrane is POLARISED- difference In charge
Voltage across membrane when it’s at test id called resting potential
What is the difference in charge called ?
Potential difference
Voltage
What is the normal number for resting potential ?
-70 mV
How is the resting potential created and maintained ?
Sodium potassium pump
And
Potassium ions channels
What type of transport/ diffusion does the sodium potassium pump use ?
Active transport - ATP needed
3 sodium ions out of neurone
2 potassium ions in
What type of transport/ diffusion does the potassium ions channels use ?
Facilitated diffusion of potassium ions out of neurone down conc gradient
Stage one
The sodium potassium pump pumps 3 sodium ions out of membrane.
The membrane isn’t permeable to sodium ions so they cannot diffuse back in membrane.
This creates sodium ion electrochemical gradient - conc gradient of ions as more postive ions located outside of membrane than inside
Step 2
The sodium potassium pump also pumps 2 potassium ions into membrane
Step 3
The potassium ions channels are open at resting state so potassium diffuses out of membrane but can also diffuse back through as membrane is permeable to potassium