1. Intro to Genomics

Question 1

What is genomics?

Answer 1

Study of the entire DNA sequence that contains the complete set of genes for an organism

Question 2

What is Genetics?

Answer 2

Study of how traits are passed down the generations and the role of genes in that process

Question 3

How do you get a protein from DNA?

Answer 3

DNA is transcribed into RNA.

RNA is translated into protein.

Question 4

What is transcriptome and proteome?

Answer 4

• Transcriptome: total RNA content

- Proteome: total protein content produced

Question 5

What is transcriptomics?

Answer 5

Study off all RNA transcripts produced by a cell, tissue, organism

Question 6

What is NGS, SNPs and GWAS?

Answer 6

NGS: next generation sequencing
SNPs: Single nucleotide polymorphisms
GWAS: Genome-wide association study

Question 7

Relationship between microarrays and NGS.

Answer 7

• Microarrays were used before NGS.
• Microarrays are still used sometimes because they’re cheaper. (But NGS is becoming cheaper overtime).
• Microarrays are used to carry out GWAS.

Question 8

Other genomes

Answer 8

• Mitochondrial
• Epigenome: changes in marks on DNA and histones.
• Metagenome : genomes of all the organisms from a specific location.