1 - Intro to Autonomic Pharmacology Flashcards

1
Q

The nervous system is made of the _____ & _____

A

Central Nervous System & Peripheral Nervous System

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The Peripheral Nervous System is made of the _______ & _______

A

Afferent & Efferent Divisions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The Efferent Division of the PNS is made of the _______ & ________

A

Somatic Nervous System & Autonomic Nervous System

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The Autonomic Nervous System is made of the ____, ____, & _____

A

Sympathetic, Parasympathetic, & Enteric Nervous Systems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

-mimetic

A

drug that mimics the action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

-lytic

A

drug that blocks or terminates the action of corresponding system in the ANS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

-ergic

A

refers to work or action; used to describe the action of the corresponding neurotransmitters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The sympathetic nervous system has (short/long) preganglionic nerves & (short/long) postganglionic nerves

A

Short, Long

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The ______ nervous system has more thoracolumbar outflow & the _______ nervous system has more craniosacral outflow

A

Sympathetic, Parasympathetic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Do all organs have dual innervation?

A

No (exp. lacrimal glands - only parasympathetic, exp. kidney - only sympathetic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which organs only have sympathetic nervous system action?

A

Kidney, Adrenal medulla, Ureters & bladder, Genitalia, Blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which organs only have parasympathetic nervous system action?

A

Lacrimal glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A research intern has anesthetized a dog in the lab to study effect of vagal denervation. What do you expect if the vagal innervation of the heart is cut off?

A

The heart rate increases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

An ophthalmologist needs to perform a funduscopic examination to visualize the retina. The pupils have to remain dilated to ensure proper visualization. However, the light from the fundoscope would cause reflex contraction of the iris. What category of drug would achieve dilation of the iris?

A

Sympathomimetic/Parasympatholytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What neurotransmitter is used for all preganglionic neurons?

A

Acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What neurotransmitter is used for most postganglionic neurons?

A

Acetylcholine

17
Q

Cotransmitters

A

Substances released along with the primary neurotransmitter and has adjunct actions, including neuromodulation (exp. ATP & Substance P)

18
Q

What are the 2 types of Cholinoceptors?

A

Muscarinic & Nicotinic

19
Q

What are the types of Muscarinic receptors?

A

M1, M2, M3, M4, M5

20
Q

What are the types of Nicotinic receptors?

A

Nm, Nn

21
Q

What amino acid is needed in adrenergic transmission?

A

Tyrosine

22
Q

What enzyme forms NE?

A

Tyrosine hydrolase

23
Q

What enzymes metabolize NE?

A

MAO & COMT

24
Q

What are the predominant co-transmitters for adrenergic receptors?

A

ATP & Substance P