1 Homeostasis

Question 1

What are the three types of signalling molecules?

Answer 1

• Endogenous – Within the body

- Exogenous I – Natural

- Exogenous II – Synthetic

Question 2

Identify 5 examples of physicochemical parameters under homeostatic control

Answer 2

• Temperature
• pH
• O₂
• CO₂
• H₂0

Question 3

Identify the two ways in which homeostasis can act and provide examples

Answer 3

• Synergistically e.g. temperature – skin blood supply & sweating
• -* Antagonistically e.g. insulin vs glucagon signal

Question 4

Why does there need to be precise temperature regulation in our bodies?

Answer 4

• Most proteins operate optimally at 37°C
• At higher temperatures, enzymes denature
• Homeostasis reduce rate of thermal degradation of proteins

Question 5

Define homeostasis:

Answer 5

tendency towards relatively stable equilibrium between interdependent elements maintained by physiological processes

Question 6

What are G-protein coupled receptors?

Answer 6

Large family- protein receptors

Detect molecules outside cell and activate internal responses

Question 7

Define membrane potential

Answer 7

Asymmetric distribution of ions across membranes

Question 8

What occurs at a neuromuscular junction?

Answer 8

Electrical communication–> muscle contraction

Question 9

What is Pharmacodynamics?

Answer 9

What the drug does to the body (target/protein)

Question 10

What is Pharmacokinetics?

Answer 10

What the body does to the drug