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Hema-Immuno > 1 - Hematopoiesis > Flashcards

1 - Hematopoiesis Flashcards

0
Q

Megakaryopoiesis

A

Platelet development

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1
Q

T-cell markers

A

CD3, CD2, CD5, CD4/CD8

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2
Q

Programmed cell dreary

A

Apoptosis

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3
Q

Formation and development of formed elements of blood

A

Hematopoietic

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4
Q

Factory of blood cells

A

Bone marrow

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5
Q

Formation and development of RBC

A

Erythropoiesis

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6
Q

Life span of RBC

A

~120 days

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7
Q

Reduced oxygen carrying capacity

A

Anemia

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8
Q

Formation of leukocyte

A

Leukopoiesis

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9
Q

Formation of basophils, eosinophils and neutrophils

A

Granulopoiesis

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10
Q

Earliest form of granular leukocytes

A

Myeloblast

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11
Q

Hematopoietic response for HYPOXIA

A

RBC production

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12
Q

Hematopoietic response for INFECTION

A

Granulocyte

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13
Q

Hematopoietic response for ANTIGEN

A

Lymphocyte

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14
Q

Hematopoietic response for hemorrhage

A

Platelets

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15
Q

Phases of erythropoiesis

A
  1. Ribosome development
  2. Hemoglobin accumulation
  3. Ejection of nucleus and formation of reticulocytes
16
Q

B-cell and T-cell maturation

A

Lymphopoiesis

17
Q

Regulated by thrombopoietin

A

Megakaryopoiesis

18
Q

Biconcave anucleated discs

A

Erythrocytes

19
Q

Immature red blood cells

A

Reticulocytes

20
Q

Minute biconvex anucleate cells

A

Platelets

21
Q

Arises from fragmentation of cytoplasm of the megakaryocytes from the bone marrow

A

Platelets

22
Q

Spherical in bloodstream but pleiomorphic ameboid cells in tissues

A

Leukocytes

23
Q

Granular leukocytes

A

Eosinophils, neutrophils, basophils

24
Q

Nongranular leukocytes

A

Lymphocytes and monocytes

25
Q

Polymorphonuclear leukocytes

A

Neutrophils

26
Q

First line of defense against infection by bacteria

A

Neutrophils

27
Q

Supplement the function of mast cells in immediate hypersensitivity reactions by migrating to tissue

A

Basophil function

28
Q

Humoral immunity

A

B cells

29
Q

Cellular immunity

A

T cells

30
Q

Types of T cells:

A
  1. Cytotoxic T cells or Killer cells
  2. Helper T cells
  3. Suppressor T cells
31
Q

Further stimulates B lymphocytes to produce antibodies

A

Helper T cells

32
Q

Largest WBC in normal blood

A

Monocytes

33
Q

Process antigens and present them to lymphocytes

A

Monocyte function

34
Q

Defense against viruses in blood, and clean-up (phagocytosis) in BM and tissue

A

Monocyte function

35
Q

Maintains colloid osmotic pressure of blood

A

Albumin

36
Q

Most abundant plasma protein

A

Colloid

37
Q

Fluid matrix in which blood cells are suspended

A

Plasma

38
Q

Composition of blood plasma:

A
  1. Water - 90%
  2. Proteins - 8%
  3. Other solutes - 2%

Hema-Immuno (2 decks)

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