1. Health at Work Flashcards
Sulsky - Stimulus definition
event of situation (stressor) in the environment that contributes to disruptive experiences. Focus: external forces. occupational stress meant negative environment factors associated with job. Ex: long commuting, high-stress job.
Sulsky - Response definition
Reaction the organism has to stressors; the nonspecific response to any demand. Strain = long term or chronic changes in response to stressor. Response always internal, however trembling hands possible or increased heart rate
Sulsky - Stimulus-response definition
Interactive. Stress as a result from INTERACTION environmental stimuli (stressor) and individual response. KEY: some stressor, environment, provokes immediate psychological appraisal this determines whether and to what extent the stressor is stressful.
Sulsky - General Adaption Syndrome
(1) alarm stage: heart beating, (2) stage of resistance: stressor prolonged resist to maintain arousal, (3) Exhaustion: body resources depleted.
McEwen - Brain structure impaired stress
Repeated stress affect the hippocampus. Episodic and declarative memory, memory of context. Impairment lowers the reliability of this and to the degree to which an event is perceived as stressful. + The hippocampus is also a stress response regulator, and it has a primarily inhibitory effect on the HPA stress response, allowing it to shut down.
McEwen - Allostasis
adaptive response in which one adaptive to something.
McEwen - allostatic load
wear and tear on body and brain resulting from chronic overactivity or inactivity of physiological systems normally involved in adaptation to environmental influences
McEwen - systems involved in coping and adaptation
Cardiovascular, metabolism, immunesystem and CNS. if not able to turn of –> load on body.
McEwen - anticipation
includes psychological states (worry, fear) as cognitive preparation. likely that this results in allostatic charge.
McEwen - health-damaging and health-promoting behaviors
smoking, drinking, diet, exercise = overall notion of allostasis. how individuals cope with a challenge and they also contribute in some ways to allostatic load (rich diet -> diabetes, smoking -> high blood pressure etc.)
McEwen - types of psychological reactions to allostatic load
frequent stress: how often reactions, failed shut down: chronic activity or failed shut down, inadequate response: failure to respond
McEwen - cardiovascular
response to challenge: avoid black-out. problems with chronic or inactivity: hypertension, stroke, MI
McEwen - metabolic
acute response: maintaining energy reserves, to brain. problems chronic or inactivity: obesity, diabetes, atherosclerosis
McEwen - immune
actue response: response to pathogens. problems chronic or inactivity: inflammatory, autoimmune disorders
McEwen - brain, CNS
acute response: learning, memory. problems chronic or inactivity: neuronal atrophy, death of nerve cells.
McEwen - how does immune system respond to acute and repeated stress?
acute stress: redistribute immune cells -> to battle stations and allostasis = response -> adaptation, reinforces responses w/ immunological memory. if this is for pathogen -> result of stress beneficial. if this is for autoimmune/allergic response -> stress effect likely to disease process. Allostatic stress suppresses ability of immune system to respond to stressors -> limitation of adaptive responses.
McEwen - conclusion
Immune system is balanced so that the response to acute stress promote adaptation and survival by protecting the body from damage. however, when systems are overworked, capacity to respond acutely with DHT is suppressed. repeated stress can cause beneficial suppression of unfavorable autoimmune response. lack of adequate allostatic HPA response to acute stress w/ increased susceptibility to autoimmune response
McEwen - characteristics habituation
ex. public-speaking -> response: increased salivary cortisol, get used to with repetition. people who do not get used to it have low self-esteem.
McEwen - frequent stress
Post-traumatic stress disorder is an example of how an acute traumatic event leads to an HPA axis that may not respond adequately to acute challenge. blood pressure surges not only trigger myocardial infarction (MI) in susceptible individuals but their repetition also accelerates atherosclerosis and primes the risk for MI.
McEwen - failed shut-down
blood pressure elevations in repetitive, time-pressured work. persisently elevated blood pressure and glucocorticoids accelerate obesity and Type II diabetes; persistent glucocorticoid elevation and/or excitatory activity in the brain causes dendritic atrophy and neuronal death in the hippocampus