1. DSA Cancer Pharmacology

Question 1

All of the following are what kind of cancer agents?
cyclophosphamide, mechlorethamine, melphalan, chlorambucil
carmustine/streptozocin (nitrosureas)
thiotepa
busulfan
procarbazine, dacarbazine, bendamustine
cisplatin, carboplatin, oxaliplatin (platinum analogs)

Answer 1

Alkylating Agents

Question 2

All of the following are what kind of cancer agents?
methotrexate, premetrexed, pralatrexate (antifolates)
5-FU, capecitabine, TAS-102 (fluoropyrimidines)
cytarabine, gemcitabine (deoxycytidine analogs)
6-mercaptopurine, 6-thioguanine, fludarabine, cladribine

Answer 2

Antimetabolites

Question 3

All of the following are what kind of cancer agents?
vinblastine, vincristine, vinorelbine
paclitaxel, docetaxel, cabazitaxel, ixabepilone, eribulin (taxanes/anti-microtubule drugs)
etoposide, topotecan, irinotecan

Answer 3

Natural Products- his favorite group

Question 4

All of the following are what kind of cancer agents?
doxorubicin, daunorubicin, idarubicin, epirubicin, mitoxanthrone, *dexrazoxane (anthracyclines)
mitomycin C, bleomycin

Answer 4

Anti-tumor Antibiotics

Question 5

All of the following are what kind of cancer agents?

imatinib, dasatinib, nilotinib, bosutinib, ponatinib

Answer 5

Tyrosine Kinase Inhibitors (small molecule)

Question 6

All of the following are what kind of cancer agents?
cetuximab, panitumumab, necitumumab, erlotinib, afatinib, osimertinib, bevacizumab, ziv-aflibercept, ramucirumab, sorafenib, sunitinib, pazopanib

Answer 6

Growth Factor Receptor Inhibitors