1. Ch 1 - Reproductive Basics Flashcards

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1
Q

excess levels of BhCG indicate

A

twins, hydatidiform mole, choriocarcinoma, embryonal carcinoma

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2
Q

inadequate levels of BhCG indicate

A

ectopic, threatened abortion, missed abortion

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3
Q

which BhCG subunit is specific? which is related to LH, FSH, and thyrotropin

A

B is specific. A is shared

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4
Q

BhCG peaks at how many weeks

A

9-10

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5
Q

BhCG is produced by

A

placental synctiotrophoblasts

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6
Q

which pregnancy hormone antagonizes insulin

A

human placental lactogen

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7
Q

progesterone is produced where

A

corpus luteum - luteal cells

9+ weeks - exclusively by placenta

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8
Q

Name the Estrogen

nonpregnant reproductive years
Follicle - Granulosa

A

Estradiol

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9
Q

Name the Estrogen

Pregnancy
Placenta - from fetal adrenal DHEAS

A

Estriol

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10
Q

Name the Estrogen

Post Menopause
Adipose - from adrenal steroids

A

Estrone

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11
Q

bluish discoloration of cervix/vagina due to increased vascularity in pregnancy

A

Chadwick sign

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12
Q

blotchy pigmentation of the nose/face in pregnancy

A

Chloasma

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13
Q

A Systolic/Diastolic ejection murmur is normal during pregnancy

A

Systolic

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14
Q

pH change normal is pregnancy

A

respiratory alkalosis

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15
Q

name the hormone

promotes the growth of ducts in the breast

A

estrogen

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16
Q

name the hormone

stimulates development of milk producing alveolar cells

A

progesterone

17
Q

name the hormone

stimulates milk production

A

prolactin

18
Q

name the hormone

causes milk ejection

A

oxytocin

19
Q

period of greatest teratogenic risk

A

3-8 weeks

20
Q

name the drug causing these birth defects

midfacial hypoplasia, long philtrum

A

alcohol

21
Q

name the drug causing these birth defects

T shaped uterus, vaginal adenosis, predispo for vaginal clear cell carcinoma

A

Diethylstilbestrol (DES)

22
Q

name the drug causing these birth defects

craniofacial dysmorphism, mental retardation, microcephaly

A

Dilantin

23
Q

name the drug causing these birth defects

congenital deafness, microtia

A

Isotretinoin (Accutane)

24
Q

name the drug causing these birth defects

Ebstein’s anomaly

A

Lithium

25
Q

name the drug causing these birth defects

teeth discoloration after 4 months

A

Tetracycline

26
Q

name the drug causing these birth defects

Phocomelia, limb reduction defects

A

thalidomide

27
Q

name the drug causing these birth defects

Neural tube defects

A

Valproic acid (Depakote)

28
Q

name the drug causing these birth defects

Chondrodysplasia

A

Warfarin

29
Q

name the genetic syndrome

primary amenorrhea, web neck, streak gonads

A

Turner syndrome

30
Q

name the genetic syndrome

testicular atrophy, gynecomastia, azoospermia

A

Klinefelter syndrome

31
Q

name the genetic syndrome

short stature, mental retardation, endocardial cushion cardiac defects

A

Down syndrome

32
Q

name the genetic syndrome

rocker bottom feet, clenched fists

A

Edward - trisomy 18

33
Q

name the genetic syndrome

cyclopia, proboscis, holoprosencephaly, cleft lip/palate

A

Patau - trisomy 13