1. Ch 1 - Reproductive Basics Flashcards
excess levels of BhCG indicate
twins, hydatidiform mole, choriocarcinoma, embryonal carcinoma
inadequate levels of BhCG indicate
ectopic, threatened abortion, missed abortion
which BhCG subunit is specific? which is related to LH, FSH, and thyrotropin
B is specific. A is shared
BhCG peaks at how many weeks
9-10
BhCG is produced by
placental synctiotrophoblasts
which pregnancy hormone antagonizes insulin
human placental lactogen
progesterone is produced where
corpus luteum - luteal cells
9+ weeks - exclusively by placenta
Name the Estrogen
nonpregnant reproductive years
Follicle - Granulosa
Estradiol
Name the Estrogen
Pregnancy
Placenta - from fetal adrenal DHEAS
Estriol
Name the Estrogen
Post Menopause
Adipose - from adrenal steroids
Estrone
bluish discoloration of cervix/vagina due to increased vascularity in pregnancy
Chadwick sign
blotchy pigmentation of the nose/face in pregnancy
Chloasma
A Systolic/Diastolic ejection murmur is normal during pregnancy
Systolic
pH change normal is pregnancy
respiratory alkalosis
name the hormone
promotes the growth of ducts in the breast
estrogen
name the hormone
stimulates development of milk producing alveolar cells
progesterone
name the hormone
stimulates milk production
prolactin
name the hormone
causes milk ejection
oxytocin
period of greatest teratogenic risk
3-8 weeks
name the drug causing these birth defects
midfacial hypoplasia, long philtrum
alcohol
name the drug causing these birth defects
T shaped uterus, vaginal adenosis, predispo for vaginal clear cell carcinoma
Diethylstilbestrol (DES)
name the drug causing these birth defects
craniofacial dysmorphism, mental retardation, microcephaly
Dilantin
name the drug causing these birth defects
congenital deafness, microtia
Isotretinoin (Accutane)
name the drug causing these birth defects
Ebstein’s anomaly
Lithium
name the drug causing these birth defects
teeth discoloration after 4 months
Tetracycline
name the drug causing these birth defects
Phocomelia, limb reduction defects
thalidomide
name the drug causing these birth defects
Neural tube defects
Valproic acid (Depakote)
name the drug causing these birth defects
Chondrodysplasia
Warfarin
name the genetic syndrome
primary amenorrhea, web neck, streak gonads
Turner syndrome
name the genetic syndrome
testicular atrophy, gynecomastia, azoospermia
Klinefelter syndrome
name the genetic syndrome
short stature, mental retardation, endocardial cushion cardiac defects
Down syndrome
name the genetic syndrome
rocker bottom feet, clenched fists
Edward - trisomy 18
name the genetic syndrome
cyclopia, proboscis, holoprosencephaly, cleft lip/palate
Patau - trisomy 13
