1- cell compartments and cytoskeleton Flashcards

1
Q

3 domains of life

A

bacteria, archae, eukaryotes

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2
Q

Prokaryotes

A

No nucleus

bacteria and archae

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3
Q

Eukaryotes

A

Nucleus

Fungi, plants and animals

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4
Q

Prokaryotic cells FEATURES

size,

A
Bacterial cells generally 1-5 um
Highly diverse
No distinct nucleus 
e.g. vibrio cholerae 
Plasma membrane, DNA ( loose ) ribosomes, cell wall, can have flagellum
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5
Q

Bacteria - dangerous, harmless?

A

Many human diseases are caused by bacteria e.g. cholera, typhoid , samonella

Some live harmlessly in our bodies - commensalism bacteria

Others are beneficial to health e.g. gut bacteria

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6
Q

Eukaryotic cells

A

10-50um or larger
Contain a nucleus and many ohter membrane bound compartments called organelles
Diverse in structure and size( even within one organism )

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7
Q

cell polarity

A

Cell polarity refers to the intrinsic asymmetry observed in cells, either in their shape, structure, or organization of cellular components.

Most epithelial cells, migrating cells and developing cells require some form of cell polarity for their function

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8
Q

The cytoskeleton

A

Network of protein filaments that runs throughout the cytoplasm of eukaryotic cells
3 main types
Provides structure, movement and transport inside cells

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9
Q

Actin filaments

A

Can grow and shrink by adding or removing actin subunits from ends
Dynamic
Smallest
Change cell shape and cause movement
Form cellular extensions e.g. microvilli
Involved in muscle contraction

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10
Q

3 proteins that make up the cytoskeleton

A

Actin filaments
Microtubules
Intermediate filaments

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11
Q

Microtubules

A

Thicker than actin filaments
Hollow cylinders of tubulin subunits ( alpha and beta )
Extend from the centrosome near the nucleus
Pull apart chromosomes during cell division
Form flagella and cilia
Provide tracks fro transport of molecules or organelles using motor proteins : kinesines= outward transport and dyneins = inward transport, important in neurones with their long axons

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12
Q

Intermediate filaments

A

Size between microtubules and actin filaments
Monomers twist to form rope like filaments found throughout cytoplasm
Provide mechanical strength for the cell = prevent shearing

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13
Q

Nucelus

A

Double membrane called nuclear envelope
Contains DNA
Substances enter and exit via pores

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14
Q

Nucleolus

A

Makes ribosomes

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15
Q

Mitachondria

A

Site of ATP production during aerobic respiration

Membrane forming cristae contains enzymes used in respirationn

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16
Q

SMooth endoplasmic reticulum

A

System of membranes containing fluid filled cavities( cisternae ) that are connected to the outer nuclear membrane
No ribosomes on surface
Contain enzymes that catalyse reactions involved with lipid and carbohydrate synthesis

17
Q

rough endoplasmic reticulum

A

Like the smooth ER but coated with ribosomes
Synthesis and transport of proteins
Proteins transported to golgi apparatus for modification and packaging

18
Q

Golgi apparatus

A

Looks like smooth ER but stacks like WIFI
Vesicles at the end of cisternae
Proteins are modified e.g. by being folded into 3d shape
Packaged into vesicles that are pinched off and stored in cell or moved to plasma membrane

19
Q

Cell surface membrane

A

Phospholipid bilayer with proteins and cholesterol
Barrier between cell and its surroundings, selectively permeable so controls what enters and leaves the cell
Site of cell cell recognition and recieving of cell signals

20
Q

Lysosomes

A

Specialised vesicles surrounded by a single membrane
Engulfs old cell organelles, water materials and foreign matter and return digested components to cell for reuse
Role in apoptosis

21
Q

Vesicles

A

Membranous sacks surrounded by single membrane and fluid inside
Transport materials inside the cell and have storage roles

22
Q

Ribosomes

A

Made of rRNA

Synthesising proteins

23
Q

Cytosol

A

Aqueous portion of cytoplasm

24
Q

Cytoskeleton functions

A

Organelles held in place
Controls cell movement and contraction
Organelle movement

25
Q

Peroxizome

A

Where oxidation occurs

26
Q

Centrioles

A

2 centrioles form the centrosome