1- cell compartments and cytoskeleton Flashcards
3 domains of life
bacteria, archae, eukaryotes
Prokaryotes
No nucleus
bacteria and archae
Eukaryotes
Nucleus
Fungi, plants and animals
Prokaryotic cells FEATURES
size,
Bacterial cells generally 1-5 um Highly diverse No distinct nucleus e.g. vibrio cholerae Plasma membrane, DNA ( loose ) ribosomes, cell wall, can have flagellum
Bacteria - dangerous, harmless?
Many human diseases are caused by bacteria e.g. cholera, typhoid , samonella
Some live harmlessly in our bodies - commensalism bacteria
Others are beneficial to health e.g. gut bacteria
Eukaryotic cells
10-50um or larger
Contain a nucleus and many ohter membrane bound compartments called organelles
Diverse in structure and size( even within one organism )
cell polarity
Cell polarity refers to the intrinsic asymmetry observed in cells, either in their shape, structure, or organization of cellular components.
Most epithelial cells, migrating cells and developing cells require some form of cell polarity for their function
The cytoskeleton
Network of protein filaments that runs throughout the cytoplasm of eukaryotic cells
3 main types
Provides structure, movement and transport inside cells
Actin filaments
Can grow and shrink by adding or removing actin subunits from ends
Dynamic
Smallest
Change cell shape and cause movement
Form cellular extensions e.g. microvilli
Involved in muscle contraction
3 proteins that make up the cytoskeleton
Actin filaments
Microtubules
Intermediate filaments
Microtubules
Thicker than actin filaments
Hollow cylinders of tubulin subunits ( alpha and beta )
Extend from the centrosome near the nucleus
Pull apart chromosomes during cell division
Form flagella and cilia
Provide tracks fro transport of molecules or organelles using motor proteins : kinesines= outward transport and dyneins = inward transport, important in neurones with their long axons
Intermediate filaments
Size between microtubules and actin filaments
Monomers twist to form rope like filaments found throughout cytoplasm
Provide mechanical strength for the cell = prevent shearing
Nucelus
Double membrane called nuclear envelope
Contains DNA
Substances enter and exit via pores
Nucleolus
Makes ribosomes
Mitachondria
Site of ATP production during aerobic respiration
Membrane forming cristae contains enzymes used in respirationn