1 Basic Concepts Flashcards
What are the 3 major components with a similar developmental origin?
Bone
Skeletal muscle
Connective tissues
What are the functions of bone?
Support Protection Metabolic (Ca, P) Storage (fat) Movement Haematoopoeisis
What are the functions of skeletal muscle?
Locomotion Posture Metabolic (store glycogen) Venous return Heat production Continence
What are tendons?
Contain lots of collagen, little elastin
Don’t stretch much
Connect muscle to bone
What are ligaments?
Support bone to bone
What are fascia?
Sheets of connective tissue
Used for compartmentalisation of muscle
Protection
Superficial fascia fatty
What is the role of articular cartilage in bone?
Hyaline cartilage
Slippery to decrease friction
Blue/grey
What is the role of fibrocartilage in bone?
Shock absorption
Increase bone congruity
Stronger than articular
Found in knee
What is the role of the synovial membrane?
Secretes synovial fluid for joint and tendon lubrication
What is the bursa?
Synovial fluid-filled sacs to protect tendons, ligaments etc from friction
Why is CaPO4 present in ECM of bone/connective tissue?
Calcified
Gives bone strength
Contributing to compressive strength
What is the role of collagen in ECM of bone?
Gives high tensile strength
What are the roles of osteoblasts?
Build bone
Lay down osteoid
What are the roles of osteoclasts?
‘Macrophage’ of bone
Dissolve away bone to liberate Ca2+
Multinucleated
What are osteocytes?
Trapped osteoblast in bone
Detect force owing through bone
What are the 5 types of bone?
Long bone Short bone Flat bone Irregular bone Sesamoid bone