1. ACS Flashcards
PP
Most commonly due to underlying CVD
Atherosclerosis of coronary arteries that supply heart
Thrombus breaks off and occludes a coronary artery causing ischaemia
Rarely due to other causes such as acute coronary vasospasm
What does the RCA supply?
RA
RV
Inferior aspect of LV
Posterior septum
What does the left circumflex artery supply?
Left atrium
Posterior aspect of left ventricle
What does the left anterior descending artery supply?
Anterior aspect of left ventricle
Anterior septum
How can the 3 ACS syndromes be diffrentiated?
If have troponin rise and ST elevation or LBBB treat as STEMI
If have troponin rise and ST dep, T wave inversion, or deep Q waves treat as NSTEMI
Normal ECG and normal troponin = unstable angina or other cause
SS ACS
Chest pain for more than 15m
Radiates to shoulder, jaws, arms, back
N&V
Sweating
Heamodynamic instability (90/60) - Syncope
Feeling of impending doom
SOB
Palpitations
Who may have an ACS w/o chest pain?
Silent MI seen in diabetics
In the chest, the heart is positioned so the anterior heart is LA + LV.
Which artery supplies most of the anterior heart?
Which limb leads does this correspond to?
LAD artery
V1-V4
Which artery supplies the lateral heart?
Which leads does this correspond to?
Circumflex artery supplies lateral heart
1, AVL, V5, V6
Which artery supplies the inferior aspect of the heart and which leads does this correspond do?
RCA
2, 3, avf
Tests and Investigations for suspected ACS after acute management at the bedside?
Look for cause of chest pain: CV/ Resp/ GI/ exam, MSK and psych
All obs
Name 3 thrombolytic agents for NSTEMI
What is the significant side effect ass/ w/ them?
Alteplase
Tenecteplase
Streptokinase
Significant risk of bleeding
STEMI acute treatment
If present within 2h of symtom onset eligible for PCI = STEMI
If present later thrombolysis
NSTEMI acute treatment
BATMAN
Beta blocker (eg. lisinopril)
Aspirin 300mg
Ticagrelor 180mg
Morphine tritated to control pain
Anticoagulant = fondaparinux
Nitrates- GTN
GRACE score + PCI if medium or high risk of repeat ACS in next 6m
Which classification is used to assess whether PCI is required in ACS?
GRACE classification
Used to assess risk of death or repeat MI 6m after having an ACS
Under 5% = low
5-10% = medium
Over 10% = high
Used to guide who needs more intensive care + consider PCI within 4 days if medium or high risk and had NSTEMI